Introduction: -Lactams are among the most widely prescribed antibiotics in human medicine. However, because of their massive and usually inappropriate use, resistance to these drugs has increased markedly, especially due to extended-spectrum -lactamase (ESBL) production. Objectives: The aims of this study were to determine the prevalence of urinary Escherichia coli strains isolated from urine samples taken from patients diagnosed with urinary tract infections (UTIs), to evaluate their current antimicrobial susceptibility pattern and to look for blaSHV, blaTEM and blaCTX-M genes in these multi-drug resistant isolates. Subject and methods: A retrospective survey was made over 3 years from 2010 to 2012. It included all uropathogenic E. coli strains isolated from urine samples taken from consulting and hospitalized patients in the Avicenne Teaching Hospital in Marrakech, Morocco. Results: E. coli was the etiologic agent in 63% of reported UTIs due to Enterobacteriacae. In all, the prevalence of ESBL-producing E. coli reached 6% of all urinary Enterobacteriaceae isolates in 2012.
We report a case of human immunodeficiency virus type 1 group O infection not detected by two highly sensitive immunoassays. The sera were strongly reactive to the V3 peptide of group O but not to the gp41 immunodominant epitope. Gp41 was sequenced, confirming that this virus belonged to group O.
La cellulite cervico-faciale grave est une infection polymicrobienne extensive et redoutable du tissu cellulo-adipeux de la face et du cou. L'objectif de cette étude est d'analyser certains facteurs favorisants et d’évaluer les critères de gravité en fonction des formes anatomo-cliniques. Il s'agit d'une étude rétrospective réalisée, entre janvier 2007 et décembre 2012, au service de chirurgie maxillo faciale de l'hôpital militaire Avicenne de Marrakech. Sur 147 cas de cellulites cervico-faciales pris en charge au niveau du service, 13 dossiers de cellulites graves ont été retenus. Neuf hommes (69%) et quatre femmes (31%) ont fait l'objet de cette étude, avec un âge moyen de 35 ans. Tous les patients ont été adressés pour prise en charge secondaire après avoir pris des anti-inflammatoires (AI). Sept cas (54%) étaient immunocompétents. La cause dentaire était soulevée chez neufs cas (69%). Cinq cas (38%) ont présenté une forme pseudo phlegmoneuse avec des signes compressifs des voies aéro-digestives. L'extension médiastinale a été observée chez quatre patients (31%). La forme nécrosante extensive a été retrouvée dans trois cas (23%). L’étude bactériologique, réalisée chez tous les patients, avait mis en évidence une flore microbienne mixte et polymorphe. Les cellulites cervico-faciales graves posent un réel problème de prise en charge thérapeutique. L'analyse des facteurs favorisants et l’évaluation des critères de gravité dans cette série ont permis de limiter une évolution défavorable.
Mosquitoes transmit several agents of diseases and the presence of different species represents a threat to animal and public health. Aedes and Culex mosquitoes are of particular concern giving their potential vector competence for Arbovirus transmission. In Morocco, the lack of detailed information related to their spatial distribution raises major concerns and hampers effective vector surveillance and control. Using maximum entropy (Maxent) modeling, we generated prediction models for the potential distribution of Arboviruses vectors (Aedes aegypti, Ae. vexans, Ae. caspius, Ae. detritus, and Culex pipiens) in Morocco, under current climatic conditions. Also, we investigated the habitat suitability for the potential occurrence and establishment of Ae. albopictus and Ae. vittatus recorded only once in the country. Prediction models for these last two species were generated considering occurrence datasets from close countries of the Mediterranean Basin, where Ae. albopictus is well established, and from a worldwide database for the case of Ae. vittatus (model transferability). With the exception of Ae. vittatus, the results identify potential habitat suitability in Morocco for all mosquitos considered. Existing areas with maximum risk of establishment and high potential distribution were mainly located in the northwestern and central parts of Morocco. Our results essentially underline the assumption that Ae. albopictus, if not quickly controlled, might find suitable habitats and has the potential to become established, especially in the northwest of the country. These findings may help to better understand the potential distribution of each species and enhance surveillance efforts in areas identified as high risk.
Arboviruses (arthropod‐borne viruses) are expanding their geographic range, posing significant health threats to millions of people worldwide. This expansion is associated with efficient and suitable vector availability. Apart from the well‐known Aedes aegypti and Ae. albopictus, other Aedes species may potentially promote the geographic spread of arboviruses because these viruses have similar vector requirements. Aedes japonicus, Ae. vexans and Ae. vittatus are a growing concern, given their potential and known vector competence for several arboviruses including dengue, chikungunya, and Zika viruses. In the present study, we developed detailed maps of their global potential distributions under both current and future (2050) climate conditions, using an ecological niche modeling approach (Maxent). Under present‐day conditions, Ae. japonicus and Ae. vexans have suitable areas in the northeastern United States, across Europe and in southeastern China, whereas the tropical regions of South America, Africa and Asia are more suitable for Ae. vittatus. Future scenarios anticipated range changes for the three species, with each expected to expand into new areas that are currently not suitable. By 2050, Ae. japonicus will have a broader potential distribution across much of Europe, the United States, western Russia and central Asia. Aedes vexans may be able to expand its range, especially in Libya, Egypt and southern Australia. For Ae. vittatus, future projections indicated areas at risk in sub‐Saharan Africa and the Middle East. As such, these species deserve as much attention as Ae. aegypti and Ae. albopictus when processing arboviruses risk assessments and our findings may help to better understand the potential distribution of each species.
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