No abstract

To evaluate the correlation between male serum anti-mullerian hormone and ICSI outcomes ( fertilization rate, cleveage rate, quality of embryos and pregnancy rate ). The type of study was controlled randomized study on fifty five infertile couples undergoing ICSI procedure at fertility center in Al-Sadder medical city in Al Najaf Al Ashraf. The research was included two groups are unexplained (n=24) and male factor infertility ( n=31)who underwent intracytoplasmic sperm injection programme. blood samples were taken from husbands to assessment of anti-mullerian hormone at day of retrieval of follicles. The results of ICSI were reported in both two groups. The correlation between male serum anti-mullerian hormone with fertilization rate, cleavege rate, and quality of embryos was studied. The current research results were revealed significant increase ( P <0.001), in concentration of male serum anti-mullerian hormone in unexplained group (7.29 ± 0.73) compared to male factor (2.36 ± 0.19 ) group. good quality embryos had significant increase (P value0.053)in unexplained group (5.70 ± 0.94) compared to male factor group(3.70 ± 0.5). Pregnancy rate was also found to be not significantly differed but the higher percentage of pregnancy (32.3%) occurred in male factor group compared to unexplained group(25%).There was positive correlation (r=0.293 p=0.03 ) between good quality embryos and male serum anti-mullerian hormone. Results of this study showed found positive correlation between male serum anti-mullerian hormone and good embryos which may lead to improvement in pregnancy rates.

Evaluation of the level of anti-sperm antibodies, some cytokines and zinc for oligozoospermia patients, asthenozoospermia patients and normozoospermia patients. Semen samples were collected from asthenozoospermic, oligozoospermic, and normozoospermic men who attended the fertility center. The collected samples of normozoospermia patients were (15), Asthenozoospermia patients were (15), and Oligozoospermia patients were (13). Seminal plasma for all study groups was evaluated for interleukin-1, interleukin-6, and zinc levels. The result showed there were statistically significant differences (p < 0.05) in sperm concentration, progressive motility, and liquefaction time in the asthenospermia and oligospermia groups compared with the normospermia group. This study found that antisperm antibody, interleukin 1, and interleukin 6 were higher in the oligozoospermia and asthenozoospermia groups than in the normozoospermia group. The levels of antisperm antibodies and interleukins increase, while zinc levels decrease in the seminal plasma of patients with oligospermia, as well as those with asthenospermia, compared to patients with normospermia.

Studying the efficiency of the swim up from pellet technique in reducing antisperm antibody and some cytokine levels in seminal plasma. Semen samples were collected from oligozoospermic and Normozoospermic who attended a fertility center. The collected samples of normozoospermia patients were (15 (and oligospermia patients were (13). antisperm antibody, interlukine-1, interlukine-6, and zinc levels were evaluated in seminal plasma before and after semen processing for all study groups. The results revealed that there was a statistically significant decrease (p < 0.05) in antisperm antibody, interleukin 1Β (IL-β), interleukin (IL-6), and zinc. After sperm preparation by swim up from pellet compared with before sperm preparation, The result illustrates there was a statistically significant decrease (p < 0.05) in sperm concentration and leucocytes count while there was significant increase (p>0.0.5) in progressive motility, normal morphology after preparation by swim up from pellet compared with before the preparation. In concluded Processing by swim-up techniques decreases sperm concentration, and also shows an increase in sperm normal morphology and progressive motility in normospermia, oligospermia, and asthenospermia groups. Antisperm antibody, interleukin 1 (IL-), interleukin 6 (IL-), and zinc levels are all reduced.