Studying the efficiency of the swim up from pellet technique in improving sperm parameters and reducing the levels of antisperm antibody and interleukins for infertile men

Abstract

Studying the efficiency of the swim up from pellet technique in reducing antisperm antibody and some cytokine levels in seminal plasma. Semen samples were collected from oligozoospermic and Normozoospermic who attended a fertility center. The collected samples of normozoospermia patients were (15 (and oligospermia patients were (13). antisperm antibody, interlukine-1, interlukine-6, and zinc levels were evaluated in seminal plasma before and after semen processing for all study groups. The results revealed that there was a statistically significant decrease (p < 0.05) in antisperm antibody, interleukin 1Β (IL-β), interleukin (IL-6), and zinc. After sperm preparation by swim up from pellet compared with before sperm preparation, The result illustrates there was a statistically significant decrease (p < 0.05) in sperm concentration and leucocytes count while there was significant increase (p>0.0.5) in progressive motility, normal morphology after preparation by swim up from pellet compared with before the preparation. In concluded Processing by swim-up techniques decreases sperm concentration, and also shows an increase in sperm normal morphology and progressive motility in normospermia, oligospermia, and asthenospermia groups. Antisperm antibody, interleukin 1 (IL-), interleukin 6 (IL-), and zinc levels are all reduced.