Evaluation the level of antisperm antibodies, some cytokines and zinc for oligozoospermia, asthenozoospermia patients compared with normozoospermia

Abstract

Evaluation of the level of anti-sperm antibodies, some cytokines and zinc for oligozoospermia patients, asthenozoospermia patients and normozoospermia patients. Semen samples were collected from asthenozoospermic, oligozoospermic, and normozoospermic men who attended the fertility center. The collected samples of normozoospermia patients were (15), Asthenozoospermia patients were (15), and Oligozoospermia patients were (13). Seminal plasma for all study groups was evaluated for interleukin-1, interleukin-6, and zinc levels. The result showed there were statistically significant differences (p < 0.05) in sperm concentration, progressive motility, and liquefaction time in the asthenospermia and oligospermia groups compared with the normospermia group. This study found that antisperm antibody, interleukin 1, and interleukin 6 were higher in the oligozoospermia and asthenozoospermia groups than in the normozoospermia group. The levels of antisperm antibodies and interleukins increase, while zinc levels decrease in the seminal plasma of patients with oligospermia, as well as those with asthenospermia, compared to patients with normospermia.