Coumarin is a heterocyclic scaffold and its derivatives namely Schiff bases, esters, and hydrazides, etc, play an
important role in the field of agrochemical and pharmaceutical industry due to its structure. Over the years, various biological
activities like antifungal, antimicrobial, anti-viral, anti-cancerous, anti-tumor, anti-inflammatory, anti-filarial, enzyme
inhibitors, anti-aflatoxigenic, analgesics, antioxidant and Oestrogenic, etc had been analyzed. This review covers the latest
literature and knowledge on the synthetic procedures for various coumarin and its derivatives, biological and pharmacological
applications.
Semicarbazide hydrochloride is proposed as an efficient absorbing reagent for the fixation of atmospheric sulphur dioxide. The proposed reagent has an absorption efficiency of ca. loo%, is non-toxic and is readily available in a pure form. After absorption, the amount of sulphur dioxide is determined spectrophotometrically, using p-aminoazobenzene and formaldehyde in acidic medium. The pink dye has a maximum absorption at 505 nm. The interference of nitrogen dioxide is much less than in other reported methods. The method has been successfully applied to the determination of sulphur dioxide in environmental samples.
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