Coriandrum sativum L. (coriander), an everyday spice in the Indian kitchen is known to add flavor to the cuisine. It is an annual herb belonging to the Apiaceae (Umbellifera) family. The hydro-alcohol extract of Coriandrum sativum L. at the dose of 1 mg/ml was subjected to a series of in vitro assays viz. 2, 2′-diphenyl-1-picrylhydrazyl, lipid peroxidation by thiobarbituric acid, reducing power and nitric oxide (NO) radical scavenging in order to study its antioxidant efficacy in detail. The amount of flavonoids in 70% ethanol extract was found to be 44.5 μg and that of the total phenols was 133.74 μg gallic acid equivalents per mg extract. The extracts of the leaves showed metal chelating power, with IC 50 values, 368.12 μg/ ml where as that of standard EDTA was 26.7 μg/ml. The IC 50 values for 2, 2′-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid radical scavenging was 222 μg/ml where as that of standard ascorbic acid was 22.6 μg/ml. The NO scavenging activity of the extract of the leaves showed IC 50 value of 815.6 μg/ml; at the same time the standard BHA had 49.1 μg/ml. All the plant extracts provided DNA damage protection; however, the protection provided at the dose of 8 μg/ml was comparable to that of standard gallic acid. The Coriandrum sativum leaf extract was able to prevent in vitro lipid peroxidation with IC 50 values; 589.6 μg/ml where as that of standard BHA was 16.3 μg/ml. Our results also showed significant ferric reducing power indicating the hydrogen donating ability of the extract. This study indicated the potential of the leaf extract as a source of natural antioxidants or nutraceuticals that could be of use in food industry with potential application to reduce oxidative stress in living system.

No abstract

The hydro alcohol extract rich in Polyphenols and other secondary metabolites is a potent anxiolytic agent.

No abstract

Lactuca sativa (lettuce) belongs to Asteraceae family important leafy vegetable known for its medicinal properties. The lettuce is a food that should not lack in our meals, we should keep in mind that its low fat and carbohydrate contents and its high contents of water, it provides caloric power of only 13 Kcal /100 gm are very appropriate for weight loss diets. It is rich in minerals, especially potassium that is very necessary to maintain appropriate levels of liquids in the body, together with calcium and phosphorus makes it especially for the correct well being of the bones. It contains selenium, an antioxidant that has a medicinal property in prevention of certain type of cancers, colon, prostrate and lungs. It contains many necessary amino acids for the formation of the proteins, alanine, and necessary for the construction of muscular and nervous tissues, glycine for the correct operation of immunological system. The most of therapeutic properties of this plant is due to sesquiterpene lactones-lactucin, lactucopicrin the most bioactive compound of Lactuca sativa. This review mainly focuses on the pharmacological action of the Lettuce and active constituents for the wide spectrum biological properties, such as anti-oxidant, anti-inflammatory, anti-microbial, analgesic, neuroprotective and sedative properties, etc. Since Lettuce has medicinal therapeutic potential its usage in dietary supplementation can be exploited. Lettuce has also acquired a folk reputation. More clinical studies are needed to further asses the efficiency and safety in therapeutic application.

No abstract

Ayurvedic way of diagnosis has two basic components mainly Rogapariksha and Rogipariksha. Among them Rogapariksha gives us the detailed knowledge about a disease starting from the etiological aspects to the actual manifestion of disease. The five basic components of Rogapariksha are Nidana, Purvarupa, Rupa, Samprapti and Upashaya, which are collectively known as Nidana Panchakas. Nidana, the foremost component among them not only gives the knowledge of causative factors but also helps in treatment by avoiding them. Among all the Indriyas, Netra is said to be Pradhana, thus a special care and concern should be taken to protect it. Understanding the strength of the causative factors for eye diseses will help to execute the treatment appropriately and maintain the healthy vision. Thus an attempt is made to analyse the Netra Roga Nidana in this presentation.

Background: Coriandrum sativum L. (coriander) is an annual herb belonging to the Apiaceae family, used for medicinal purposes. Objective: To investigate the effect of the hydroalcoholic extract obtained from Coriandrum sativum leaves on the exploratory behaviour pattern and locomotor activity of mice. Materials and Methods: Elevated plus maze (EPM) and open field test (OFT) were the screening tests used to assess the anxiolytic activity of , the extracts on mice. Diazepam (1 mg / kg) served as the standard anxiolytic agent. The animal receiving extracts or diazepam showed an increase in the time spent, total entries in the open arm of the EPM and increased total locomotion in the OFT, suggesting anxiolytic activity. Results: The crude dried extract was prepared in doses of 100, 200 and 400 mg / kg body weight and administered intraperitoneally to the mice, for evaluation of the anxiolytic activity. The 200 and 400 mg / kg body weight produced highly significant (P < 0.01) anxiolytic effects, in a dose-dependent manner, by increasing the time spent on and the number of entries into the open arms of the EPM and by an increase in the locomotion by mice in the OFT. Furthermore, in lower doses the extract did not affect the locomotor activity. Conclusion: Our findings demonstrated that the leaf extract of the plant exerted an anti-anxiety effect on mice in the elevated plus maze and open field test.