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I rhe protective efficacy of a well-known calcium channel blocker, Verapamil, against Mipafox, a protbtype of nervt gas, has been investigated. Mipafox is a potent organophosphorus ester which has both acute and :delayed neurotoxic effects. The results of the present study indicate that as an adjunct to Atropine, Verapamil shows protective action in overcoming the delayed neurotoxic effects. However, it m~kes either.little or no contribJtion to the recovery of the acute toxic effects of Mipa(ox. I I 1.