Incidence of unusually high numbers of stillbirths was observed at a piggery unit at the Veterinary University research farm in Tamil Nadu State of India. Systematic examination of the tissue from stillborn piglets led to the identification of presence of Porcine circovirus 2 (PCV2). Detailed analysis utilizing electron microscopy, polymerase chain reaction and sequencing confirmed the presence of PCV2 in the tissue of affected piglets. Histopathology analysis of the affected piglet tissue showed lymphoid cell depletion of lymphnodes, spleen and infiltration of liver, kidney, myocardium, etc. Retrospective examination of the morbidity and mortality history in the farm revealed high mortality in young and weanling piglets suggestive of PCV2 infection-induced diseases. This is the first report of emergence of major disease incidence in farmed swine due to PCV2 infection in India.
Epulis fissuratum also called as Denture-induced hyperplasia (DIH) is a tumor-like hyperplasia of fibrous connective tissue, which develops in association with an ill-fitting complete or partial denture. Virchoft first invented the term “Epulis” and the meaning is “over the gums”. However the use of this term is not appropriate as it emphasizes only the actual site of the lesion. In most cases, the affected mucosa is usually the oral mucosa of the vestibular sulcus or the palatal region. Therefore, “Denture-induced fibrous hyperplasia” was considered to be a much-preferred term. This is a case report of an 65 year old female with a history of wearing complete denture for 2 years and ended up in developing multiple proliferative growths.
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