Objective-Although most cigarillos and little cigars smokers also smoke cigarettes (dual use), there are few studies comparing toxicant exposure and smoking behavior in cigars and cigarettes.Methods-Two groups of dual users smoked their usual brand of cigarette and either a Winchester unflavored little cigar (N = 21) or a Black & Mild cigarillo (N = 23). Acute exposure of nicotine and exhaled carbon monoxide (CO) and puffing topography parameters were collected. Individual cigar puffing data were used to machine-replicate smoking for analysis of volatile organic compounds (VOC) and semi-volatile organic compounds (SVOC) in mainstream smoke.Results-There were significant differences in puff topography, plasma nicotine and exhaled CO after cigarettes, little cigars, and cigarillos. Puff topography differences between cigarillos and cigarettes were due to the difference in the size of the article. Mainstream cigar and cigarette smoke was qualitatively similar; the yield was dependent on the smoking behavior. When smoke yield was adjusted for weight of tobacco burned or puff volume, exposure differences decreased.Conclusions-There is a wide range of delivery of both SVOC and VOC components of cigar and cigarillo smoke. The difference in exposure is largely dependent on the article size and the amount consumed.Correspondence Dr Koszowski; koszowskib@battelle.org. Human Subjects StatementThe study was approved by Battelle's Institutional Review Board. Conflict of Interest StatementThe authors have no conflicts of interest to declare. Another impediment has been that off-the-shelf commercial smoking topography instrumentation and hardware is designed for cigarette research and must be modified to accommodate cigar products. HHS Public AccessA further challenge is that cigars (unlike cigarettes) come in a wide variety of sizes -from articles the size of cigarettes containing less than 1g of tobacco to large cigars that may contain 30g of tobacco filler. 4 Furthermore, there are idiomatic use patterns associated with some cigar smoking that are not seen in cigarette smoking. For example, partial smoking and re-lighting is common among cigarillo smokers 5 but almost never seen among cigarette smokers. Other studies 6-8 and the Internet document the practice of "hyping" -removing the tobacco filler and the paper liner and repacking the filler before smoking some cigarillo brands; chewing on the tip; and using cigars to deliver marijuana. 9,10 Also, little cigar and cigarillo consumers typically use both a cigar product and a conventional cigarette (dual users). 2,5,[11][12][13] Although there are practical challenges to research and some questions on the generalizability of results, the use of laboratory smoking studies provide an estimate of the use behavior and toxicant exposure. We have adopted puff topography methods and measures of acute toxicant exposure developed and used in cigarette studies 14,15 to investigate cigarillo and little cigar smoking in our laboratory. Replicated human puffing measures were use...
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