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Objectives: Objectives: The antioxidant potential of gossypin and nevadensin, two flavonoid compounds, were evaluated by in vitro methods. Materials and Methods: Materials and Methods: Gossypin, nevadensin, and the reference standard, butylated hydroxyl toluene (BHT), were evaluated for DPPH (1, 1-diphenyl-2-picrylhydrazyl), nitric oxide, superoxide, and hydroxyl radical scavenging activity. Results: Results: Gossypin and BHT showed the potential for significant DPPH radical inhibition of up to 88.52 and 91.45% at 100 µg/ml concentration. With a 100 µg/ml concentration of gossypin, the in vitro nitric oxide, superoxide, and hydroxyl radical scavenging activity was found to be 74.00, 74.22, and 67.15%, respectively; and with 100 µg/ml of BHT the corresponding values were 82.24, 81.76, and 73.03% of inhibition, respectively. Conclusion: Conclusion: The study results showed that gossypin has significant antioxidant activity.

A simple, specific and accurate reverse phase high performance liquid chromatographic method was developed for the determination of Belinostat in pharmaceutical dosage form. The column used was ALTIMA C18, 150 x 4.6 mm, 5 with mobile phase containing Buffer and Acetonitrile were taken in the ratio of 40:60 the flow rate was 1.0 mL/ min and eluent was monitored at 266nm. The retention time of Belinostat was 2.320 min. The linearity of the drug was designed at a range for which correlation coefficient was 0.999. The proposed method was validated and successfully applied to the estimation of Belinostat in formulations. Forced degradation studies were conducted to identify reactions which may occur to degrade a processed product.

Purpose: To investigate the anti-inflammatory and analgesic activities of the Amorphophallus 16, 2.66 and 8.16 (p < 0.001) and 8.5 (p < 0.001)

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