RESUMO Avaliaram-se os efeitos da associação de fentanil e droperidol sobre a freqüência cardíaca (FC) e eletrocardiografia (ECG), em cães submetidos à anestesia pelo desflurano. Para tal

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The aim of this study was to compare the effects of desflurane, sevoflurane and isoflurane on pulmonary shunt in dogs during spontaneous ventilation. General anesthesia was induced in 30 healthy, adult, mongrel dogs by intravenous administration of propofol. The animals were separated into three groups of 10 dogs each and submitted to general inhalation anesthesia with 1.5 MAC of desflurane (G1), sevoflurane (G2) and isoflurane (G3). Arterial blood was collected by puncture of the right femoral artery, and mixed blood was collected by introducing a Swan-Ganz catheter into the pulmonary artery. These samples were used to determine the parameters employed for calculation of the intrapulmonary shunt. Measurements began at 20min after orotracheal intubation and were repeated every 20min, totaling six measurements. Means were compared by the Student t-test (P<FONT FACE=Symbol>£</FONT> 0.05). Desflurane led to a higher shunt than sevoflurane and isoflurane at 40 and 60min. At 80min, the mean values obtained for desflurane were higher than those obtained for isoflurane, while at 100min the values observed for dogs anesthetized with desflurane were higher than those obtained with sevoflurane. Desflurane caused respiratory depression by reducing PaO2, and a higher percentage of intrapulmonary shunt than isoflurane and sevoflurane.

The purpose of this study was to evaluate periodontal disease (PD) in dogs with chronic renal failure (CRF) and to compare it to PD in dogs with normal renal function (NRF). Twelve dogs with CRF and 24 dogs with NRF, all presenting dental pocket formation, were compared. In all dogs, serum creatinine, blood urea nitrogen, urine specific gravity and total red and white blood cells were determined. A complete oral examination was also performed including evaluation of bacterial plaque, gingivitis, gingival recession, pocket, calculus, dental mobility, dental loss, and ulcers. These data were used to calculate plaque index (PI), gingival index (GI) and periodontal destruction index (PDI). PD was graded as mild, moderate or severe based on the results. Mild, moderate or severe PD was observed in dogs with NRF, whereas dogs with CRF presented either mild or severe PD. Dogs with NRF showed higher involvement of the maxillary teeth, whereas dogs with CRF showed a higher involvement of the mandibular teeth. Plaque index was significantly higher in dogs with NRF. It was concluded that lesion distribution and periodontal disease progression may be altered in dogs with CRF, and gingival inflammatory response differs in dogs with NRF and CRF regarding to the stage of periodontal disease.

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