Background:Musa seminifera Lour is a tree-like perennial herb that has been used in folk medicine in Bangladesh to heal a number of ailments.Objective:To evaluate the antioxidant, analgesic, antidiarrheal, anthelmintic activities, and general toxicity of the ethanol extract of the roots.Materials and Methods:The extract was assessed for free-radical-scavenging activity by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, total phenolic content (TPC) by the Folin Ciocalteu reagent, antioxidant activity by the ferric reducing power assay, analgesic activity by the acetic acid-induced writhing and hot-plate tests, antidiarrheal activity by the castor oil-induced diarrhea model in mice, anthelmintic activity on Paramphistomum cervi and Haemonchus contortus, and general toxicity by the brine shrimp lethality assay.Results:The extract showed free-radical-scavenging activity with an IC50 value of 44.86 μg/mL. TPC was 537.89 mg gallic acid equivalent/100 g of dried plant material. It showed concentration-dependent reducing power, and displayed 42.11 and 69.32% writhing inhibition at doses of 250 and 500 mg/kg body weight, respectively. The extract also significantly raised the pain threshold at the above-mentioned dose levels. In vivo antidiarrheal property was substantiated by significant prolongation of latent period and decrease in total number of stools compared with the control. The LC50 against brine shrimp nauplii was 36.21 μg/mL. The extract exhibited dose-dependent decrease in paralysis and death time of the helminths.Conclusion:The above results demonstrated that the plant possesses notable bioactivities and somewhat supports its use in folk medicine.
Pigeon farming, like chicken and duck farming, is getting popularity nowadays in Bangladesh. The present study was conducted on the postnatal development and morphometry of egg of different breeds of pigeon available at northern Barind tract of Bangladesh. The study was conducted at thirty selected pigeon farms of three districts (Rajshahi, Natore and Pabna) of northern Barind tract of Bangladesh. The postnatal development (weight gain of squabs) of five groups (D0, D7, D14, D21, D28; D=day), and morphometry of eggs (egg weight, egg width (short axis), and length (long axis)) of breeds of pigeon (n=20, each breed) available at northern Barind tract in Bangladesh were collected and analyses with Duncan's Multiple Range test (DMRT). Considerable differences in the postnatal weight gain and egg morphometry were found among breeds of pigeon. The mature body weight of Giribaz, Kormona, Nun and Owl breeds of pigeon were below 300 gm; Satinette, Mookee, Suachandan, Lakkha, Jacobin, Bokhara, Shirajee, Homer and Pouter were 300-500 gm, and King and Strasser were below 800 gm. The postnatal weight of an age group was significantly different (p<0.05) from other age groups of all studied breeds. The highest egg length was 4.37±0.02 cm in Strasser, and the lowest was 3.68±0.01 cm in Giribaz pigeon. The highest egg width was 3.24±0.19 cm in Mookee, and the lowest was 2.73±0.02 cm in Giribug pigeon. The highest egg weight was 21.20±0.49 gm in Strasser, and the lowest was 14.00±0.23 gm in Owl pigeon. Moreover, a relationship between the body weight and egg length, width and weight of pigeons was observed in pigeons of all studied breeds. Asian J. Med. Biol. Res. September 2020, 6(3): 594-598
Spermatogonial stem cells (SSCs) are the most primitive spermatogonia in the testis. A balance between the self-renewal and differentiation of SSCs, strictly controlled in a special „niche‟ microenvironment in the seminiferous tubules (SSC niche), is essential to maintain normal spermatogenesis. Since the 1950s, many experimental methods, including histology, immunostaining, whole-mount analyses, and pulse-chase labeling, had been used in attempts to identify SSCs. Recent studies demonstrate that Aundiffseem to possess variable levels of stem cell potential to act as SSCs; GFRα1+ population in As has the greatest potential to act as SSCs (can consider as actual SSCs) whereas NGN3+ population in Aundiffhas comparatively much lower potential to act as SSCs (can consider as potential SSCs). The precise identity of SSCs is still being refined. Sertoli cells, directly interact with SSCs, and interstial cells including Leydig cells, testicular macrophages, peritubularmyoid cells and vascular smooth muscle cells, control the proliferation and differentiation of SSCs through the secretion of extrinsic factors, constitute the cellular components of SSC niche which preferentially locates in the region of seminiferous tubules adjacent to the interstitium that always coincide blood vessels. Asian J. Med. Biol. Res. September 2020, 6(3): 375-382
Performance evaluation of existing dairying is important to design relevant dairy development strategies and implement context specific interventions for future development of the dairy enterprise. The present study was carried out to evaluate the clinical trends (reproductive performance and disorders) of dairy cows of Rajshahi district, Bangladesh. A total of 500 cows randomly selected and data were collected directly from the dairy farms owners from 6 upazilas and 4 metro thanas of Rajshahi district by using questionnaires and diagnosis of reproductive disorders (RD) was made on the basis of history, clinical signs and response to treatment. The average reproductive performance (RP) were recorded as age at puberty 26.42±0.22 m, age at first calving 35.48±0.22 m, post-partum heat period 121.85±3.48 days, service per conception 1.93±0.04, days open 136.80±3.57 days and calving interval 401.04±3.94 days. The better RP was found at metro thanas compared to upazilas, though no significant difference was found except on service per conception (p<0.05). The overall prevalence of RD was 78.6% in Rajshahi district. Among the reproductive and productive disorders, anoestrus 24.6% was the highest prevalent disorders followed by abortion 13.4%, repeat breeding 11.4%, retained placenta 10.2%, dystocia 5.4%, mastitis 4.4%, vaginal prolapse 2.4%, pyometra 1.8%, metritis 1.6%, uterine prolapse 1.4%, milk fever 1.2% and still birth 0.8%. The highest occurrence of RD was recorded in Tanore upazila (92%) and the lowest in Poba upazila (62%). In comparison between the upazila and metro thanas the minimum occurrence of RD was recorded in metro thanas (31%) than upazilas (47.6%). Asian J. Med. Biol. Res. June 2020, 6(2): 340-350
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.