Introduction: There is a wide spectrum of salivary gland lesions with morphologically and clinically diversity which is a difficult task for histopathological interpretation. There are three major salivary glands-parotid, submandibular, and sublingual as well as minor salivary glands distributed throughout the mucosa of the oral cavity. Neoplastic and non-neoplastic disease may develop within any of these. Aims: (1) To study the histopathological features of salivary gland lesions, (2) To study the prevalence of salivary gland lesions in tertiary care hospital, (3) To evaluate the incidence, age at the occurrence, and sex ratio among the patients with salivary gland lesions, (4) To compare the result of our study with other studies. Material and Method: Retrospective study was done from January 2016 to June 2018. The study was done on 55 specimens from patients with salivary gland lesions which are referred to the Department of Pathology from Department of ENT and Surgery, P.D.U. Medical college, Rajkot. Salivary gland specimens were immediately fixed in 10% formalin and processed by paraffin embedding. Sections were stained by hematoxylin and eosin stain. Finally, microscopic examination was done to diagnose Result: In present study, out of 55 cases, 05 cases (9.1%) were inflammatory, 41 cases (74.5%) were benign and 09 cases (16.4%) were malignant. Most common benign tumor of salivary gland was pleomorphic adenoma followed by Warthin's tumor. Most common malignant tumor of salivary gland was mucoepidermoid carcinoma. Conclusion: Histopathological study of salivary gland lesions is the most important method in establishing the final diagnosis and subtyping. Salivary gland tumors are relatively less common and they exhibit a wide variety of microscopic appearances even within one particular lesions.
Background: Safety for blood Transfusion begins with healthy donors. A basic part of preventing transfusion transmitted infections (TTIs) is to notify and counsel reactive donors. This study analysed trends in the prevalence of transfusion-transmissible infectious pathogens among blood donors and notify them as well as to assess response rate among them. Donor notification and counselling protect the health of the donor and stop secondary transmission of infectious diseases.
Methods: 38707 blood donations were screened for TTIs, namely, HIV, HBV, HCV, and syphilis, Malarial Parasite by serology. ELISA testing for anti-HIV antibody, anti-HCV antibody and HBsAg and RPR test for syphilis, Rapid card test for Malarial Parasite. All reactive donors were retested in duplicate and notified of their status by communicating through telephone.
Result: We evaluated 341 (0.88%) cases with reactive screening test results (0.617% HBV, 0.016% HCV, 0.134% HIV, 0.08% syphilis, 0.031% Malaria ). Only 179 donors (52.5%) responded to notification. The response among voluntary donors was better as compared to the replacement donors (54.1 % versus 40.7 %). Only 101 (57.22%) responsive donors followed their first attendance at referral clinic.
Conclusion: Our study provides prevalence rate of TTIs among blood donors and importance of proper donor counselling and notification of TTI status to all reactive donors who opt to receive this information.
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