Os autores relatam um caso de condrossarcoma em uma paciente de 14 anos portadora de osteocondromatose múltipla, que procurou assistência médica com a queixa de tumoração na coxa esquerda. Cortes tomográficos do membro afetado evidenciaram lesão osteodestrutiva no terço superior do fêmur esquerdo. O diagnóstico foi feito através da revisão da lâmina do serviço de origem da paciente, confirmando o achado de condrossarcoma grau I em lesão condromatosa. Foi realizada desarticulação do colo femoral devido ao extenso comprometimento de grupos musculares, de tecido celular subcutâneo e de pele. A literatura mostra ampla variação nas taxas de transformação maligna das exostoses em pacientes portadores desta doença, sendo esta uma importante complicação nestes pacientes.

Authors' contributions: DAD: equal contributions to the design or development of the study; to the collection, analysis and interpretation of data; to the writing of the article and its critical revision; to the approval of the final version. LAB: design or development of the study. LON: approval of the final version. RGSP: writing of the article. OABJ: data collection, analysis and interpretation of data. JWLTJ: equal contributions to the design or development of the study; the collection, analysis and interpretation of data; the writing of the article and its critical revision; and the approval of the final version.

No período de 1992 a 1998, foram avaliados, retrospectivamente, exames de tomografia computadorizada e prontuários de 22 pacientes com carcinoma espinocelular de corda vocal. Avaliou-se a concordância entre observadores para todos os casos e a acurácia e concordância entre os métodos para os casos operados, utilizando-se o índice kappa. A concordância foi excelente para o comprometimento tumoral das cartilagens tireóide, cricóide, extensão extralaríngea e estadiamento linfonodal; ótima para o envolvimento tumoral das cordas vocais, comissura posterior e espaço paraglótico; boa para o envolvimento tumoral da supraglote, subglote e estadiamento tumoral; regular para o envolvimento tumoral da comissura anterior e cartilagem aritenóide. A utilização simultânea da avaliação clínica e tomográfica para o estadiamento T obteve acurácia e concordância com achados patológicos de 89,47% e 84,9%, respectivamente, sendo superior à análise clí-nica isolada ou tomográfica. A acurácia e concordância patológica da tomografia computadorizada para o estadiamento N foi de 100%, sendo superior à avaliação clínica. Unitermos: Carcinoma espinocelular. Corda vocal. Tomografia computadorizada.Computed tomography evaluation of loco-regional involvement of squamous cell carcinoma of the vocal cord. We reviewed the case notes and computed tomography scans of 22 patients with squamous cell carcinoma of the vocal cord, in the period between 1992 and 1998. Interobserver concordance for all cases and accuracy and concordance between the methods for the operated patients were evaluated using the kappa test. Concordance was classified as follows: excellent for evaluating tumoral involvement of the thyroid and cricoid cartilages, extralaryngeal extension and lymph node staging; very good for tumoral involvement of vocal cords, posterior commissure and paraglottic space; good for tumoral involvement of the supraglottic and subglottic regions and tumoral staging; regular for tumoral involvement of the anterior commissure and arytenoid cartilage. The combination of clinical and computed tomography evaluation for T staging resulted in an accuracy and concordance with the pathological results of 89.47% and 84.9%, respectively, which were superior to isolated clinical or computed tomography analysis. The accuracy and pathological concordance of computed tomography for N staging was 100%, which was superior to clinical evaluation. nóstico dos pacientes(1) . É desejável, especialmente nestes casos, além do tratamento apropriado objetivando a cura oncológica, oferecer a capacidade de fonação e deglutição de modo razoável. A avaliação clínico-endoscópica e os mé-todos de imagem têm a responsabilidade de demonstrar, da forma mais precisa possível, a real extensão neoplásica, avaliando o possível comprometimento de estruturas relevantes ao planejamento terapêutico (2) . É função do radiologista avaliar adequadamente a extensão tumoral, contribuindo com informações importantes. O comprometimento linfonodal cervical também influencia a conduta e o prognóstico...

Honey is the most widespread bee product in the world. Consumption-centered research supports the honey market, subsidizing marketing strategies focused on consumer’s profile. The present manuscript was aimed at providing a bibliometric analysis and a systematic review of scientific production on honey consumption. The data comprise periodical articles indexed in the Web of Science - Clarivate Analytics, processed in the VOSviewer software. A total of 472 articles with the radicals honey* consum* in the bibliometric analysis were identified. The manuscripts come from 68 countries, published between 1958 and 2018, with the largest number of publications in 2016 (52). Of the 472 articles initially retrieved, the reading of titles and abstracts revealed 22 specific papers about honey consumption. These articles comprise 14 countries. Their objectives included: to characterize the profile of the consumers, reasons that lead to the purchase and consumption of honey, perceptions about the market price, socioeconomic effects on the consumption pattern, among other aspects. However, the low number of articles identified in the systematic review reveals a gap still present in the literature on honey consumption. Despite the large number of articles originally identified at WoS database, the systematic revision revealed out the scarcity of publications directly dealing with honey consumption in their objectives, the number of which has been increasing from 2006 onwards. The results also showed that most research on honey consumption were based on quantitative methods, especially the use of face-to-face interview for data collection, which reveals a potential for further studies focused on these approaches. Poland and the United States stood out with the major countries with articles on honey consumption, although the lack of such studies for countries with large honey production (such as China, Iran and Turkey). Finally, regarding to the country of origin of the authors, a low internationalization of scientific literature on this research issue was also observed.

Background: There is no consensus on how recognition of universal facial emotions can be affected in low-educated individuals with Alzheimer’s Disease (AD). Objective: To assess the performance of Facial Recognition of Emotions Test (FERT) and to correlate with patterns of cortical atrophy measured through Voxel-Based Morphometry (VBM) in low-educated individuals with mild AD dementia compared to cognitively healthy people. Methods: Retrospective cohort of 24 adult volunteers with 4 years of schooling or less were included. Among them, 13 participants had a diagnosis of mild AD. Data obtained by VBM and FERT result were correlated. Results: AD group had a worse performance in the total FERT score (p <0.001). There was a statistically significant difference in the recognition of surprise, disgust and neutrality (p <0.001). A more intense and consistent correlation was observed between the volume of the Accumbens Area (AA) and FERT performance in the total group (r=0.817 and p <0.05). This correlation remained significant for emotion “disgust” only in the AD group (r=0.769 and p <0.05). Conclusion: We found a significant difference in the recognition of surprise, disgust and neutral emotions between groups. The brain region that was most associated with these emotions was the AA, with greater consistency in the difficulty in recognizing the emotion of disgust, in the AD.

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