Researchers have a range of animal models in which to study Nonalcoholic fatty liver disease (NAFLD). Induction of NAFLD by a high-fat diet in the C57BL/6 strain is the most widely used among mice. In this study, we review works that performed NAFLD induction by a high-fat diet using the C57BL/6 strain, focusing on experiments on the effects of lipid ingestion. Studies are initially distinguished into researches in which mice received lipids by oral gavage and studies in which lipid was added to the diet, and each of these designs has peculiarities that must be considered. Oral gavage can be stressful for animals and needs trained handlers but allows accurate control of the dose administered. The addition of oils to the diet can prevent stress caused to mice by gavage, but possible changes in the consistency, taste, and smell of the diet should be considered. Regarding the experimental design, some variables, such as animal sex, treatment time, and diet-related variables, appear to have a definite pattern. However, no pattern was found regarding the number of animals per group, age at the beginning of the experiment, time of adaptation, the substance used as a vehicle, and substance used as a control.

Resumo: O aproveitamento de frutos no desenvolvimento de produtos visa inserir no mercado alimentos com um maior aporte de nutrientes, estimulando assim, hábitos de vida mais saudáveis. Os frutos do Cerrado possuem um grande potencial econômico e nutricional, entretanto se faz necessária a busca por alternativas para um maior aproveitamento e conservação desses frutos. Diante do exposto, o objetivo deste trabalho foi caracterizar quimicamente geleia de bocaiuva (Acrocomia aculeata) acrescida de maracujá (Passiflora edulis), por meio dos parâmetros: sólidos solúveis, acidez titulável, pH, Aw, sólidos totais, fenóis totais, atividade antioxidante, taninos, carotenoides e ácido ascórbico. A polpa de bocaiuva utilizada na elaboração da geleia também foi caracterizada devido aos diferentes morfotipos encontrados no Estado de Mato Grosso do Sul. A geleia de bocaiuva com maracujá apresenta 106,01 mg g -1 de fenóis totais, 466,55 de g g -1 de DPPH, 4,94mg 100g -1 de taninos, 11,44 mg 100g -1 de carotenoides. A polpa de bocaiuva apresenta 240,8 mg g -1 de fenóis totais, 261,14 de g g -1 de DPPH, 10,66 mg 100g -1 de taninos e 58,29 mg 100g -1 de carotenoides. A geleia de bocaiuva com maracujá reteve os compostos considerados bioativos em sua composição, provenientes das polpas de bocaiuva e de maracujá. Palavras-chave: Acrocomia aculeata; cerrado; compostos bioativos.Abstract: The use of fruits in the development of products aims to insert in the market foods with a greater contribution of nutrients, thus stimulating, healthier life habits. The Cerrado fruits have great economic and nutritional potential, however, it is necessary to search for alternatives for a better use and conservation of these fruits. The objective of this work was to characterize the chemical composition of bocaiuva jelly (Acrocomia aculeata) and passion fruit (Passiflora edulis), using soluble solids, titratable acidity, pH, Aw, total solids, total phenols, antioxidant activity, tannins, carotenoids and ascorbic acid. The pulp of bocaiuva used in the elaboration of the jelly was also characterized due to the different morphotypes found in the State of Mato Grosso do Sul. The jelly of bocaiuva with passion fruit presents 106,01 mg g -1 of total phenols, 466,55 g g -1 DPPH, 4.94 mg 100g -1 tannins, 11.44 mg 100g -1 carotenoids. The bocaiuva pulp shows 240.8 mg g -1 total phenols, 261.14 g g -1 DPPH, 10.66 mg 100 g -1 tannins and 58.29 mg 100 g -1 carotenoids. The bocaiuva jelly with passion fruit retained the compounds considered bioactive in their composition, derived from the pulp of bocaiuva and passion fruit.Resumen: El aprovechamiento de frutos en el desarrollo de productos busca insertar en el mercado alimentos con un mayor aporte de nutrientes, estimulando así, hábitos de vida más saludables. Los frutos del Cerrado poseen un gran potencial económico y nutricional, sin embargo, se hace necesaria la búsqueda de alternativas para un mayor aprovechamiento y conservación de estos frutos. En el presente trabajo se analizó la relación entre el peso de...

Metabolic syndrome (MetS) and obesity are growing in many parts of the world, becoming public health problems. It is proposed that foods with functional properties can assist in the treatment of these diseases. Crude buriti pulp oil (BPO) is a food traditionally consumed by residents in the Pantanal, Cerrado and Brazilian Amazon. It is rich in oleic acid, tocopherols and carotenoids, emerging as a potential functional food. Thus, this study aimed to evaluate the effect of the supplementation of BPO on metabolic disorders caused by a high‐fat diet. Four groups of C57BL6 mice were used, a lean group with AIN‐93M diet and control oil supplementation, an obese group with a high‐fat diet and control oil supplementation, and two obese groups with a high‐fat diet and BPO supplementation in the amounts of 50 and 100 mg/kg. BPO worsened the metabolic state caused by the high‐fat diet, worsening risk factors associated with MetS, as the abdominal circumference and retroperitoneal fat, serum levels of total cholesterol, uric acid, alanine transaminase, glucose and triglycerides, and renal fat, in addition to changes in glycaemic control and oxidative stress markers. C57BL/6 mice fed with a high‐fat diet and supplemented with BPO presented a worsening in metabolic risk factors associated with MetS.

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O limiar anaeróbio (LAn) é uma variável fisiológica utilizada para auxiliar a prescrição de exercícios físicos. Diante da importância de sua determinação para saúde dos praticantes de atividade física, foi feito nesse estudo, uma revisão de literatura sobre a validade da determinação do LAn por aferição da concentração de glicose sanguínea. Foram utilizado artigos publicados nos indexadores Scielo e Pubmed, resultando na seleção de 15 artigos, entre os anos de 1999 e 2013. A literatura aponta que a determinação do LAn por aferições de glicose é estatisticamente igual a aferição por lactato sanguíneo. O LAn varia de acordo com o ergômetro em que o teste é realizado. Por fim, há indicação de que o conhecimento do LAn é fundamental tanto para praticantes de atividade física quanto para pacientes com diabete melito tipo 2, pois pode auxiliar no controle de aumentos excessivos da concentração de glicose sanguínea durante o exercício físico.

Bacuri (Attalea phalerata Mart. Ex Spreng.) is a fruit belonging to Palmae family, found in Mato Grosso do Sul - Brazil with great nutritional potential. The objective of the present study was to perform processing, elaboration, nutritional analysis and sensorial acceptability test of protein supplement formulations with bacuri almonds aiming its use by vegetarian public and sportsmen. Bacuri almonds were processed to lyophilized flour of the protein isolate, and then mixed with other ingredients to produce two supplement formulations: F1 containing 70% bacuri lyophilized almond flour, and F2 containing 35% bacuri lyophilized almond flour and 35% commercial supplement. Nutritional composition analysis, amino acid determination and sensory analysis were performed. Both supplements presented high protein content. F1 and F2 were significant different for energy, moisture, ashes, proteins and carbohydrates content. Amino acid profile was satisfactory for methionine, cysteine, phenylalanine and tyrosine for both. Sensory analysis showed acceptability indexes above the minimum limit of 70%, which is considered accepted. Thus, bacuri almond is an alternative ingredient in plant food supplements. However, its isolated use (F1) still needs further testing for sensory acceptability indices improvement.