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Summary 1. Overconsumption of fructose produces glucose intolerance, autonomic abnormalities and renal dysfunction and may be related to the worldwide epidemic of obesity and diabetes. 2. Experiments were conducted to determine whether the time period (light or dark) of fructose consumption influenced the pathological consequences. C57BL mice were given standard chow and assigned to one of three groups: (i) control (n = 10), which received water over a 24 h period; (ii) FL (n = 11), which received 10% fructose solution during the 12 h light period; and (iii) FD (n = 11), which received 10% fructose solution during the 12 h dark period. 3. There was a time related increase in body weight for all groups (P < 0.01, 2 vs 6 wks). There was a greater increase in body fat in the FL group compared with the control and FD groups. The changes in adiposity occurred even though the total caloric intake was not significantly different among the groups (approximately 18 kcal/day). Total fluid (water + fructose) consumption was greater in the FD and FL groups compared with control at 6 weeks. Significant increases were noted for plasma insulin and leptin at 8 weeks, with highest levels in the FL compared with FD group (P < 0.05). There were no significant changes in glucose, glucose tolerance, cholesterol, triglycerides or adiponectin. 4. The results of the present study suggest that there is a mismatch in caloric consumption, metabolism and adiposity as related to the light–dark cycle of fructose consumption. These findings have clinical implications in the control of bodyweight, abdominal fat accumulation and Type 2 diabetes.

The purpose of the present study was to measure the dynamic, static and rotary balance of deaf and hearing children. 20 deaf and 20 normal hearing students matched for mean age of 123 +/- 5.9 or 5.6 mo. and sex (11 boys, 9 girls) performed three tests of balance. A series of Wilcoxon signed-ranks tests and a Kendall Tau were applied to assess whether balance was affected in sensorineural deafness and to assess whether age and sex were factors in over-all balance, respectively. Significant differences were noted between groups for dynamic balance and rotary balance. Although not significant, there was a difference of 57.8% in number of trials for successful completion of static balance in favor of the hearing children. In the present study, over-all balance in deaf children was significantly inferior to the balance in hearing children. Knowledge of these differences may aid those working with deaf children in physical education.

To determine the effects of exercise and ovariectomy on calcium status in selected appendicular and axial bones, female Sprague-Dawley (8-9 mo) rats were assigned to groups based on the following combinations: control (C) or ovariectomized (O); sedentary (S) or exercised (E); and length of treatment (2 or 4 mo). Exercise consisted of treadmill running for 1 h/day, 5 days/wk at a speed of 14.1 m/min and 8 degrees elevation. After death, femurs, tibia-fibula complexes, ribs (T7), and vertebrae (T7) were excised, cleaned, and weighed, and selected morphometrics were measured. Tensile strength was measured for the femurs, and all bones were then acid-hydrolyzed and calcium concentration determined spectrophotometrically. Bone [Ca2+] was significantly greater for CE and OE animals when compared with their sedentary counterparts (CS, OS). Within 4 mo calcium losses were evident in the femur and tibia of the ovariectomized animals, and the moderate exercise program was of insufficient intensity to alter this loss. The average stress to failure for femur from all groups was 1.13 +/- 0.11 N/m2. However, the effects of exercise appeared beneficial in the axial bones where [Ca2+] increased in the ovariectomized animals.