Background: Polycystic ovarian syndrome (PCOS) is one of the most common endocrine disorders seen in infertility clinic of Gynae OPD. It is basically is disease of metabolic disorder and requires ultrasound and hormonal assay for its diagnosis.Methods: The study was carried out in the GOPD of MGM medical College and M.Y. Hospital Indore (M.P.) India. It included 200 women in the age group 18-40 years diagnosed as PCOS and who were compared with 200 women of same age group without PCOS. The height, weight BMI and waist hip ratio were measured and analyzed statistically.Results: The present study shows that women with PCOS had higher incidence of acne hirsutism and irregular menses (p<0.0001), women with PCOS had higher mean ovarian volume measurement (11±1.4cc) compared to female controls who had lower volume of ovary with a range of (7.94±2.34cc. (p<0.0001) as calculated by USG by sonologist.Conclusions: The presence of central obesity, (waist hip ratio >0.87) is an indication for presence of PCOS. Thus, these patients may undergo further hormone evaluation and this simple measurement can help to screen out PCOS from general population. This prevents financial burden on low resource settings.

Background: Preterm birth is a significant health problem across the world because of associated neonatal mortality and short-and long-term morbidity in later life. The incidence in India is higher than developed countries.Methods: The present study conducted in the Department of Obstetrics and Gynaecology, MGM Medical College and M. Y. Hospital. Indore, (Madhya Pradesh). The patients selected from labour rooms.100 antenatal women of gestational age between 28 weeks to 37 weeks presenting with preterm labor, 50 in each group. Group A consisted women receiving magnesium sulphate, group B had women receiving isoxsuprine. Efficacy of the two tocolytics, prolongation of pregnancy and neonatal outcome in preterm labour was assessed.Results: Intravenous magnesium sulphate was much effective in postponement of preterm labour for at least 48 hours (74%) as compared to isoxsuprine (50%). As a cervical dilatation, effacement increased the success rate of both the drugs came down. Magnesium sulphate side effects were better monitored clinically and tolerated. Also, better neonatal outcome and lesser perinatal mortality were noticed in this group (24%) compared to isoxsuprine (54%).Conclusions: Prematurity is the one of the major risk factor determing perinatal outcome. There is no ideal tocolytic, short term prolongation till steroid coverage for lung maturit with minimum side effects and to achieve better perinatal outcome recommended. The number of nursery admissions of preterm babies with better perinatal outcome were observed with magnesium sulphate. Also, the number of nursery admissions of preterm babies were less when treated with magnesium sulphate as tocolytic (also found to have neuroprotective effects in various studies), as compared to isoxsuprine.