An 8-year-old castrated Toy poodle presented with swelling and proptosis of the right third eyelid caused by an exophytic mass on the bulbar surface. Histologically, the mass was composed of stratified neoplastic basaloid cells, arranged in nests and interconnecting islands, which were mixed with tubular structures. Immunohistochemically, the basaloid cells were positive for p63 and cytokeratin (CK) 14, and the inner epithelial cells of the tubular structures were positive for CK7, CK8, and CK19. According to these findings, the mass was diagnosed as a basal cell adenocarcinoma. Although basal cell adenocarcinoma is rare in animals, it should be included in the list of differential diagnoses for superficial tumors of bulbar conjunctiva of third eyelid in dogs.
A slaughtered 2-year-old female sika deer (Cervus nippon yesoensis) had
diffusely distributed multinodular lesions on the serosal surface of the peritoneal cavity
and several nodules in the pleural cavity. Histologically, they were composed of
proliferating spindle-shaped neoplastic cells, arranged in a fascicular fashion. The cells
in the invasive foci transitioned from a sarcomatoid to an epithelioid appearance.
Immunohistochemically, both the spindle-shaped and epithelioid cells were at least focally
positive for pancytokeratin, vimentin, calretinin, α-SMA, and desmin. From these findings,
the deer was diagnosed with peritoneal sarcomatoid mesothelioma with metastasis to the
pleural cavity. To our knowledge, this is the first reported case of peritoneal
mesothelioma in a cervid species and the first case of mesothelioma in a sika deer.
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