day social life, the declining cost of alcohol relative to disposable income levels, a lack of public awareness of health consequences, and the liberalization of alcohol control policy on the part of many governments. The Erroll and Clayson Cominittees seem likewise to have ignored the possible public health consequences of their recommendations. By trying to keep in step with, and follow, current social trends of increasing alcohol use in England and Scotland alike, the Erroll and Clayson recommendations, if accepted by Government, may easily strengthen even further and accelerate the social acceptance of heavier alcohol use, and with it, in line with the Ontario research workers' conclusions, the risks of increased alcohol-related physical and social damage.-I am, etc.
The records of 1471 patients with ALL entered into UKALL trials II-V (1972-1977) were studied, and major bone lesions at diagnosis were recorded in 47 (3.2%). These were found predominantly in young patients (median age 5 years), equally in both sexes, and were seen to be associated with a low blood leucocyte count and prolonged remissions.
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