Selective Histopathology for Appendix Specimens

Brooks, Sara; Hughes, Richard G.M.

doi:10.1016/s0140-6736(87)91146-9

Cited by 10 publications

(13 citation statements)

References 3 publications

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“…The present review shows that the incidence Lau [32] Brooks [25] Gupta [29] Wolkomir [26] Matthijssens [9] Jones [30] Martellucci [34] Lohsiriwat [33] Overall Was histopathology valid as a reference test? Were intra-operative and histopathological examination blinded from each other?…”

Section: Discussionmentioning

confidence: 99%

“…The presence of neoplasia was also frequently missed intra-operatively, although the variation among the studies was high. Some authors claim to have diagnosed all aberrant findings intra-operatively [9,25,26] but most articles recommend routine histopathology owing to the unreliability of intra-operative diagnosis [5,10,11,[27][28][29][30][31][32][33][34]. The available data did not permit an assessment of the clinical impact of histopathological examination, because this was not reported sufficiently.…”

Section: Discussionmentioning

confidence: 99%

“…None of the studies gave adequate information on the criteria for an intra-operative or histopathological diagnosis. Due to this lack of baseline information, we decided to pool only [28] 1981 R New Zealand 3003 All specimens Chan [10] 1986 R Hong Kong 12513 All specimens Lau [32] 1986 P Hong Kong 1699 All specimens Brooks [25] 1987 R UK 653…”

Section: Study Characteristicsmentioning

confidence: 99%

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Is routine histopathological examination of appendectomy specimens useful? A systematic review of the literature

et al. 2011

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

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Is routine histopathological examination of appendectomy specimens useful? A systematic review of the literature

et al. 2011

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“…It has been suggested that routine histopathological examination of appendicectomy specimens is unnecessary and a waste of diminishing health care resources [7]. The suggestion has evoked much discussion in the literature [8].…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Accuracy in Appendicitis: A Histopathological Study

Sathar

Junaid²

2001

Med Princ Pract

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Objective: Although appendicectomy accounts for the highest number of unnecessary surgical procedures, there is little information on the accuracy of the procedure in Kuwait. Therefore, the objective of this study was to determine the accuracy of pre-operative diagnosis of acute appendicitis and the influence of age, gender and surgical personnel on the rate of normal appendicectomy. Materials and Methods: A retrospective histopathological review of specimens involving ‘acute appendicitis’ in the surgical pathology files of the Mubarak Al-Kabeer Hospital, Kuwait in 1982–1986 and 1992–1996 was carried out. The diagnostic accuracy (DA) was defined as the proportion of specimens in which an inflamed appendix was confirmed microscopically and the negative appendicectomy rate (NAR) was the proportion of appendices that were microscopically normal. Results: The DA was 80 and 84% for 1982–1986 and 1992–1996, respectively. There was a marked decline in the number of females in the second period from 42 to 30%. Females, who accounted for 36% of all cases, comprised 61% of normal appendicectomies with the highest NAR in the 20- to 29-year age group (23.7%). The NAR decreased in the second period from 18.4 to 12.4%. Conclusion: The results show that the clinical diagnostic accuracy of appendicitis in Mubarak Al-Kabeer Hospital is consistent with reports from several centres. However, auditing with routine histopathological examination is still necessary to improve clinical evaluation, particularly in females, many of whom are still subjected to the risks of unnecessary laparotomy.

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“…Previous reports in the literature focus on the advisability or not of submitting surgical specimens based on macroscopic appearance and clinical history. [7][8][9] In these, the need for histopathological assessment has been a surgical decision. It has been argued that selective submission of nasal polyps according to strict criteria misses no clinically important lesions.…”

Section: Discussionmentioning

confidence: 99%