Background: PCOS was a common hormonal disorder caused by hyperandrogenism so the ovaries enlarged with many small follicles appear like cysts. The aetiology still unknown, but mounting evidence suggests that can be complex multigenic disorder with strong epigenetic and environmental influences. Therapeutic options include combined oral contraception, antiandrogens, etc. Case Presentation: Ms. N, 17 years old, came to polyclinic of RSAL Mintohardjo evaluated for amenorrhea. Her parents didn’t have comorbid conditions. The patient started Menarche at the age of 14, soon thereafter developed a secondary amenorrhea. On examination her BMI was 18.4kg/m², pulse-92/min and BP-115/80 mm of hg. She had a hirsute score (Ferriman-Gallway) of 8 and had no acanthosis nigricans. No abnormality on the other systemic examination and no laboratory tests were carried out. Patient given with combination hormonal pills. Hormonal birth control can help with PCOS symptoms, but it is not the only option. Lifestyle changes, such as losing weight and exercising more, may help. Discussion: PCOS involves primary defects in hypothalamic–pituitary axis, insulin, and ovarian function. Excess LH levels lead to hyperandrogenism in PCOS. Conclusion: All women with abnormal menstrual patterns should be evaluated for underlying PCOS, signs of hyperandrogenism, hormone profile, and pelvic ultrasonography to visualize the ovaries. Early diagnosis and treatment can avoid potential complications. Birth control pills (combined hormonal) can used for long-term treatment in women who didn’t want to pregnant. The birth control pills may help regulate menstrual bleeding, reduce excessive hair growth and acne, and decrease the risk of endometrial cancer.
Stunting is one of the concerned nutritional problems in Indonesia and the world, with irreversible effect which caused of lack nutrition due to chronic manifestation of malnutrition with recurrent infections during the first 1000 days of a child's life. One of the interrelated factors is the mother's age at marriage that signify an impact on the mother and her born will be at greater risk stunting. This research was conducted to determine the relationship between early marriage and incidence of stunting in under-fives aged 24-59 months. This research is using an observational study with a crosssectional research design on 130 toddlers in the Grogol Petamburan District Health Center, Wijaya Kusuma Sector from September to November 2019. Samples were taken using the consecutive non-random sampling technique. Data collected by questionnaire. Data analysis using chi-square and the significance level used was 0.05. Prevalence of early marriage of 38.5% and stunting 40%. There is a significant relationship between early marriage and incidence of stunting in under-fives aged 24-59 months (p = 0.001). The relationship between early marriage and stunting in under-fives aged 24-59 months is proven.
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