Background: Congenital Rubella Syndrome (CRS) is an infection that can cause hearing loss which is commonly found in infants in Indonesia. The hearing screening of otoacoustic emission (OAE) and automated auditory brainstem response (AABR) is essential as an early screening to prevent speech and language development disorders which may reduce the social function of the patient in the future. Objective: To analyze the profile of children with CRS who suffer from hearing loss in Dr. Soetomo General Academic Hospital, Surabaya, Indonesia in 2015-2017. Materials and Methods: This research employed a descriptive retrospective study by collecting 118 secondary data from the medical records. Results: CRS was mostly found in 0-3 months age group (76 patients), and was dominated by males (62 patients). The most common signs and symptoms were congenital heart disease (49 patients), followed by hearing loss (37 patients). The serological results were mostly dominated by negative IgM and positive IgG (40 patients). The most dominant results of hearing screening test were OAE and AABR bilateral refer (45 patients). Conclusion: The profile of children with CRS suffering from hearing loss is various, depending on which country the research is conducted.
Coronavirus Disease-19 (Covid-19) is an infectious disease that has become a pandemic since March 11, 2020. PCR (Polymerase chain reaction) swab is a definitive diagnostic tool for Covid-19, because it has a high level of sensitivity and specificity. One of the symptoms of this infection is anosmia. This study aimed to determine the relationship between the symptoms of anosmia and the positive RT-PCR swab results in Covid-19 diagnostics. This study used a systematic review and meta-analysis method that was in accordance with PRISMA. From 16 articles that met the inclusion and exclusion criteria, we selected 12 articles through EPHPP that reported smell disorder among Covid-19 patients. Four reports studied whether smell disorder was independently associated with Covid-19 diagnosis. The frequency of anosmia ranged between 7,5-95%. Anosmia has high specificity for detecting Covid-19 but has low sensitivity. There was a strong relationship between anosmia symptoms and positive RT-PCR swab results. This showed that anosmia can be a marker for patients to carry out further investigations.
Background: Congenital Rubella Syndrome (CRS) is an infection that can cause hearing loss which is commonly found in infants in Indonesia. The hearing screening of otoacoustic emission (OAE) and automated auditory brainstem response (AABR) is essential as an early screening to prevent speech and language development disorders which may reduce the social function of the patient in the future. Objective: To analyse the profile of children with CRS who suffer from hearing loss in Dr. Soetomo General Hospital, Surabaya in 2015-2017. Material and Method: This research employed a descriptive retrospective study by collecting 118 secondary data from the medical records. Result. CRS was mostly found in 0-3 months age group (76 patients), and was dominated by males (62 patients). The most common signs and symptoms were congenital heart disease (49 patients), followed by hearing loss (37 patients). The serological results were mostly dominated by negative IgM and positive IgG (40 patients). The most dominant results of hearing screening test were OAE and AABR bilateral refer (45 patients). Conclusion. The result of the CRS study is different, and depends on which country the research is conducted.
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