In euthyroid women positive for thyroid peroxidase antibodies, daily levothyroxine use before or during pregnancy does not affect live birth rates (SOR: B, randomized controlled trials).
In community dwelling adults, does diet enrichment with fruit, vegetables, fish, and whole grains reduce the risk of new onset depression?
EVIDENCE-BASED ANSWERA "healthy diet" is associated with reduction in odds for clinical depression (odds ratio: 0.84) while no statistically significant association is found between the typical "Western diet" and depression (SOR: A, systematic review and meta-analysis). In addition, adherence to healthy dietary recommendations reduces the risk of depressive symptoms while a "Western diet" increases the risk of depressive symptoms.
ng/mL (clinics A, B, and C) and 131 to 150 ng/mL (clinic D). Rivaroxaban's correlation between the anti-FXa assay and PT ranged from r50.91 to r50.73, but PT was still within normal limits when with rivaroxaban concentrations of 91 to 110 ng/mL (clinic A), 51 to 70 ng/mL (clinic B), and 171 to 190 ng/mL (clinic D). Overall, the slopes of the regression lines were relatively small, showing that the PTT and APTT were not particularly responsive to DOAC concentration. This observational study was limited by not using gold standard methods to assess DOAC concentrations and that the laboratories were spread across four different facilities, allowing for variability in reagents and coagulometers used.
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