Jasminum mesnyi Hance (yellow jasmine, Family Oleaceae) belongs to an important subclass of Jasminum family whose biological
significance is under explored. The current study pertains to isolation of various solvent extracts fractions and their anti-bacterial
effects on the Gram-positive and Gram-negative bacterial pathogens. Ethanolic extract of J. mesnyi Hance leaves was subjected to
further partitioning using different solvents with increasing polarity to get different solvent fractions. Different extracts were analysed
for their phytochemical constitutents and were evaluated for their antibacterial activity against a number of diseases causing bacteria.
Diethylether fraction (DEF) showed remarkable inhibition of growth of Aeromonas hydrophila and Vibrio parahaemolyticus with inhibition
zones of 17 and 19mm, respectively at 250 μg. On the other hand, the hexane fraction (HF) was found to be more effective against
Gram- positive test bacterial pathogens (Bacillus anthracis and Bacillus subtilis) with inhibition zones of 19.6 mm and 17.5 mm,
respectively. The phytochemical screening of different test fractions revealed the predominant presence of cardiac glycosides, sterols
and terpenoids in DEF and HF, while Ethylacetate fraction (EAF) and methanol fractions (MF) were found rich in flavonoids and
phenols with moderate amount of other reference metabolites.
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