A roentgenographic study of the osseous development of newborn white and Negro infants, measured in terms of the presence or absence of the center of ossification for the cuboid bone,1 has been made in order to investigate the association between osseous development and (1) certain other criteria of maturity, namely, birth weight, crown-heel length at birth and gestational age and (2) certain maternal characteristics, namely, parity and age.As has been pointed out, the conclusions are based on the presence or absence of the center of ossification for the cuboid bone in newborn infants. The study thus classifies the infants, according to their osseous development, into two sharply defined groups: (1) those in whom the center was present at the time a roentgenogram was made and (2) those in whom the center was not present at that time. It is obvious that study of the presence or absence of a center at a stated time fails to furnish data with regard to the time when the center appears. If it was present when the roentgenogram was made there is no information as to when it appeared ; if it was absent there is no information as to when it will appear. For a group of infants in whom the center has been found to be present, data with regard to the size of the center would,

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in the city of Buffalo is reported. The problems uncovered are medical, educational, and social, and involve a need for day care services. These problems are, of course, nationwide and the methods used to deal with them have equally wide applicability.