The aim is to evaluate the effects of photobiomodulation therapy (PBMT) on the guided bone regeneration process (GBR) in defects in the calvaria of rats filled with biphasic calcium phosphate associated with fibrin biopolymer. Thirty male Wistar rats were randomly separated: BMG (n = 10), defects filled with biomaterial and covered by membrane; BFMG (n = 10), biomaterial and fibrin biopolymer covered by membrane; and BFMLG (n = 10), biomaterial and fibrin biopolymer covered by membrane and biostimulated with PBMT. The animals were euthanized at 14 and 42 days postoperatively. Microtomographically, in 42 days, there was more evident bone growth in the BFMLG, limited to the margins of the defect with permanence of the particles. Histomorphologically, an inflammatory infiltrate was observed, which regressed with the formation of mineralized bone tissue. In the quantification of bone tissue, all groups had a progressive increase in new bone tissue with a significant difference in which the BFMLG showed greater bone formation in both periods (10.12 ± 0.67 and 13.85 ± 0.54), followed by BFMG (7.35 ± 0.66 and 9.41 ± 0.84) and BMG (4.51 ± 0.44 and 7.11 ± 0.44). Picrosirius-red staining showed greater birefringence of collagen fibers in yellow-green color in the BFMLG, showing more advanced bone maturation. PBMT showed positive effects capable of improving and accelerating the guided bone regeneration process when associated with biphasic calcium phosphate and fibrin biopolymer.
Rheumatoid arthritis (RA) is a systemic autoimmune disease that primarily affects the joints. Organokines can produce beneficial or harmful effects in this condition. Among RA patients, organokines have been associated with increased inflammation and cartilage degradation due to augmented cytokines and metalloproteinases production, respectively. This study aimed to perform a review to investigate the role of adipokines, osteokines, myokines, and hepatokines on RA progression. PubMed, Embase, Google Scholar, and Cochrane were searched, and 18 studies were selected, comprising more than 17,000 RA patients. Changes in the pattern of organokines secretion were identified, and these could directly or indirectly contribute to aggravating RA, promoting articular alterations, and predicting the disease activity. In addition, organokines have been implicated in higher radiographic damage, immune dysregulation, and angiogenesis. These can also act as RA potent regulators of cells proliferation, differentiation, and apoptosis, controlling osteoclasts, chondrocytes, and fibroblasts as well as immune cells chemotaxis to RA sites. Although much is already known, much more is still unknown, principally about the roles of organokines in the occurrence of RA extra-articular manifestations.
The dental crown can be restored using the root in clinical situations where the dental remnant allows adequate anchorage by the use of an intraradicular retainer. After endodontic treatment, reconstruction of the dental anatomy depends on correct planning and the type of restoration to be used. This requires reestablishment of form and function with creation of anchoring features, avoiding detachment and favoring the distribution of forces, thus preventing fracture of the remnant due to functional and parafunctional forces applied on the tooth. This paper reports the clinical case of a patient who sought dental care for a full metal-ceramic crown with a cast metallic core with reduced length that had been detached from tooth 24. After clinical and radiographic examination, root integrity was verified. The patient was offered reconstruction with a cast metallic core of satisfactory length, providing adequate retention and support, with reutilization of the original prosthetic crown, serving as a reverse template of the coronal portion of this new core, providing reduction in costs and operational time.
RESUMOAs articulações temporomandibulares, são representadas por articulações diartrodiais bilaterais (ATMs). Seu constituinte ósseo é correspondido pela eminência articular anterior (limite anterior da ATM, proveniente do arco zigomático) e posterior, côndilo mandibular, fossa temporal (lugar de repouso do côndilo). Os tecidos moles são correspondentes a um disco articular, cápsula, e constituintes da zona bilaminar. A ATM e suas estruturas associadas desempenham um papel essencial na orientação dos movimentos mandibulares e a distribuição de tensões produzidas por tarefas diárias, tais como a mastigação, deglutição e fala. A desarmonia no funcionamento dos componentes da ATM com o sistema estomatognático atribui-se o nome de disfunção temporomandibular (DTM). As DTM´s são uma classe de distúrbios musculoesqueléticas agudas, crônicas ou degenerativas associada a deformidades morfológicas e funcionais, podendo estar associadas ou não á oclusão, trauma ou tensão emocional. Dentre as DTM's estão inseridos os desarranjos da posição discal intra-articular, sendo este categorizado de acordo com o sistema de estágios de Wilkes, incluídas nas DTM'S temos a disfunção da musculatura associada á amplitude de movimento e dor muscular conhecida como dor orofacial. Dentre os sinais e sintomas que estão mais comumente associados a ATM, estão, a dor na região da articulação temporomandibular e masseter, estalos unilaterais ou bilaterais e travamento. Caso seja confirmado o diagnóstico, deve-se considerar o tratamento multidisciplinar e tratamento conservador, poderá ser instituido, através de placas miorelaxantes, psicoterapia, técnicas de redução de stress, fisioterapia, farmacoterapia. Entretanto caso seja esgotada a possibilidade do tratamento conservador, pode-se utilizar de técnicas cirúrgicas conservadoras como de artrocentese e artroscopia e cirurgias mais invasivas como a cirurgia articular aberta com reposicionamento do disco, eminectomia, artroplastia condilar ,discectomia e condilotomia mandibular. O presente trabalho tem por objetivo realizar uma revisão da literatura acerca dos desarranjos internos da ATM e seus respectivos tratamentos, dando enfoque a correta indicação cirúrgica para tal desarranjo.
Este artigo buscou relatar a realização da remoção de uma lesão de hiperplasia fibrosa inflamatória (HFI) localizada em mucosa jugal, sobre região de papila parotídea. Para isso, o indivíduo C.A.C.C., sexo masculino, 56 anos, procurou atendimento na Clínica de Estomatologia do curso de Odontologia da Universidade de Marília – UNIMAR, tendo como queixa principal a sensação de um leve incômodo ao realizar movimentos de fala e mastigação. Então, prosseguiu-se o atendimento com o exame clínico do mesmo e, posteriormente, procedimento cirúrgico de biópsia excisional da massa hiperplásica. Em seguida, a lesão foi submetida ao exame anatomopatológico, com finalidade de confirmação do diagnóstico inicial. Conclui-se, então, ser de extrema importância a promoção da terapêutica adequada ao paciente frente as suas necessidades, uma vez que há obtenção de qualidade de vida, além do descarte da presença de lesões de caráter maligno que possam acometer de forma mais severa o indivíduo.
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