Objectives The purpose of this study is to analyze the potential benefits of aerobic exercises at different intensities in the management of pre menstrual syndrome. Methods The study design is quasi-experimental; sixtyone female subjects were randomly allocated into three groups, Group A (mild intensity), Group B (moderate intensity) and Group C (severe intensity) and the intervention were given for 6 weeks. The study setting was general community settings. The outcome measures were menstrual symptom questionnaire, VO 2 max, forced vital capacity (FVC), maximum voluntary ventilation (MVV) and lipid profile (HDL, LDL, TGL). Results There is significant decrease in menstrual symptoms in both Groups B and C. However, Group C improved with increased rate of perceived exertion. LDL levels did not change significantly but HDL, TGL, VO 2 max, FVC, and MVV improved significantly in Groups B and C, but remains significantly unchanged in Group A.Conclusions This study encourages the employment of regular, moderate intensity aerobic exercise as a potential intervention for pre menstrual syndrome.

Physical exercise has attracted increased interest in rehabilitation of oncological patients. The purpose of this paper is to review the literature and summarize the evidence of physical exercise in preventing cancer, its ability in attenuating the effect of cancer and its treatments and to provide guidelines for exercise prescription Review of recent literature by electronic search of MEDline (Pub Med), Cancer lit, Cochrane libraries, CINAHL were done using Keywords and the variables were identified and systematically evaluated. There is strong evidence for reduced risk of colorectal and breast cancer with possible association for prostate, endometrial and lung cancer with increasing physical activity. Exercise helps cancer survivors cope with and recover from treatment; exercise may improve the health of long term cancer survivors and extend survival. Physical exercise will benefit throughout the spectrum of cancer. However, an understanding of the amount, type and intensity of exercise needed has not been fully elucidated. There is sufficient evidence to promote exercise in cancer survivors following careful assessment and tailoring on exercise prescription.

Sepsis is defined as life -threatening organ dysfunction due to dysregulated host response to infection. Mortality due to sepsis is more than 30%. Early identification and early goal directed therapy in sepsis are important for good outcome. Here in this study we are trying to assess the thyroid function test and its association with clinical outcome in sepsis patients. The objective is to assess the thyroid function test among the patients presenting with sepsis. This is a Prospective study that included 70 patients admitted in Chettinad Hospital And Research Institute with sepsis.Low FT3 levels correlated significantly with the primary outcome with a cut off value of <1.13pg/ml. All the three thyroid function test (FT3, FT4, TSH) had a significant correlation with the primary and secondary outcome in subjects with sepsis. Low FT3 levels can be considered as a single independent predictive mortality marker in subjects with sepsis. Raised TSH levels can be considered as a predictive marker for requirement of ionotropic support in subjects with sepsis. In patients with Low FT4 Levels interventional procedure requirement is high.

Bickerstaff brainstem encephalitis is a neurological disease characterized by ophthalmoplegia, ataxia with disturbed consciousness which is a variant of Guillain Barre syndrome. Here we describe a atypical presentation of Bickerstaff brainstem encephalitis with overlapping Guillain Barre syndrome features.

ESRD causes changes within the daily lives of patients, creates limitations to perform activities and features a great impact on emotions and quality of life. Cognitive Impairment is common in individuals with CKD, particularly among those treated with dialysis. The aim of the study was to assess the cognitive function, complications, adherence and psychological distress in patients undergoing hemodialysis. The study included four questionnaires, 6CIT, ESRD-AQ, Kessler’s 10, MNSI. A total of 90 subjects were enrolled in the study based on the inclusion and exclusion criteria. Cognitive function was assessed using 6CIT; 19 (21.11%) subjects presented with mild impairment, and 7(7.78%) subjects with significant impairment. The psychological distress was measured using Kessler psychological distress scale K10 and 19(21.12%) subjects had mild distress, 9(10%) subjects with moderate distress and 6(6.66%) had severe psychological distress. Adherence was assessed using the End Stage Renal Disease Adherence Questionnaire (ESRD-AQ). It was found that all the 90(100%) subjects were adherent to hemodialysis attendance and medication. Hemodialysis related acute complications were assessed and it was shown that 84(93.33%) subjects had cardiovascular complications, 86(95.55%) subjects had neuromuscular complications, 72(80%) subjects had electrolyte imbalance, and 83(92.23%) subjects experienced complications like itching, sleep disorders, back pain etc. It was concluded that there would be an improvement in the QOL of subjects if there were necessary interventions & patient education in the early stages of CKD that can help in improving self-management skills of the individual subjects and prevent progression from staging 5-CKD.