Recurrence was greater with T3/4 disease compared to T1/2 disease (70% versus 60%) (p = 0.01).T1/2 disease in the <75 group was associated with fewer recurrences than <75 T3/4 disease group (p 0.001). Recurrence rates were comparable with T1/T2 disease and T3/T4 disease in the >75 years group (p = 0.190).There was no improvement in DFS with and without AC following hepatectomy in the >75 group (p = 0.161). However there was improved DFS between the <75 groups with AC and without AC (p 0.001). OS in the>75 group was improved in the group receiving AC compared to the >75 group not receiving AC (p = 0.023). Conclusions: In patients with CRLM, with advancing age, recurrence rates do not seem to be affected by the T stage. In addition, AC following hepatectomy does not appear to improve DFS survival with advancing age.
p = 0.004). Grade 2 or 3 steatosis was significantly more common in MS-HCC (53.9% vs. 11.6% in alcohol-HCC and 5% in viral-HCC). Postoperative mortality was not significantly different between the three groups. The rates of severe complications (Dindo ! 3) in MS-HCC, alcohol-HCC and viral-HCC, were 7.7%, 8.6% and 19.0%, respectively, p = 0.034. 5-years overall survival rate of MS-HCC, alcohol-HCC and viral-HCC was 71.7%, 41.5% and 39.2% months, respectively (p = 0.701). 5-years DFS rate was 54.7% in MS-HCC, 28.4% in alcohol-HCC and 19.4% in viral-HCC (p = 0.026). Conclusions: Patients in MS group presented frequently with no underlying liver cirrhosis but with moderate-severe steatosis. DFS was significantly higher in patients with MS-HCC compared with alcohol-HCC and viral-HCC.
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