Impact of surgery on long-term survival in patients with colorectal liver metastases

Abstract

Recurrence was greater with T3/4 disease compared to T1/2 disease (70% versus 60%) (p = 0.01).T1/2 disease in the <75 group was associated with fewer recurrences than <75 T3/4 disease group (p 0.001). Recurrence rates were comparable with T1/T2 disease and T3/T4 disease in the >75 years group (p = 0.190).There was no improvement in DFS with and without AC following hepatectomy in the >75 group (p = 0.161). However there was improved DFS between the <75 groups with AC and without AC (p 0.001). OS in the>75 group was improved in the group receiving AC compared to the >75 group not receiving AC (p = 0.023). Conclusions: In patients with CRLM, with advancing age, recurrence rates do not seem to be affected by the T stage. In addition, AC following hepatectomy does not appear to improve DFS survival with advancing age.