Purpose
Reactive arthritis is acute aseptic arthritis occurring 1 to 4 weeks after a distant infection in a genetically predisposed individual. It may occur after COVID-19 infection.
We summarize, in this article, the current findings of reactive arthritis following COVID-19 infection.
Methods
A literature search has been performed from December 2019 to December 2021. We included case reports of reactive arthritis occurring after COVID-19 infection. We collected demographic, clinical, and paraclinical data.
Results
A total of 22 articles were reviewed. There were 14 men and 11 women with a mean age of 44.96 + 17.47 years. Oligoarticular involvement of the lower limbs was the most frequent clinical presentation. The time between arthritis and COVID infection ranged from 6 to 48 days. The diagnosis was based on clinical and laboratory findings. The pharmacological management was based on non-steroidal anti-inflammatory drugs in 20 cases. Systemic or local steroid therapy was indicated in 13 patients. Sulfasalazine was indicated in two cases. Alleviation of symptoms and recovery were noted in 22 cases. The mean duration of the clinical resolution was 16 + 57 days.
Conclusion
The diagnosis of reactive arthritis should be considered in patients with a new onset of arthritis following COVID-19 infection. Its mechanism is still unclear.
Although pericarditis is the most prevalent cardiac involvement in systemic lupus erythematosus (SLE), cardiac tamponade is extremely infrequent notably as the first manifestation of the disease. Here we report the case of a 22-year-old woman presenting with cardiac tamponade as the initial presentation of SLE.
RésuméLa toxocarose humaine est une zoonose parasitaire cosmopolite causée par Toxocara canis et Toxocara catisqui sont des ascarides des chiens et des chats. C’est une affection le plus souvent bénigne. Nous rapportons un cas de pancréatite aigue dans le décours une toxocarose.
BackgroundRheumatoid arthritis (RA) is a chronic autoimmune disease characterized by the presence of rheumatoid factor (RF) and anti-cyclic citrullined peptide (ACPA). ACPA have higher specificity than RF for RA, and are associated with joint radiographic damage and extra-articular manifestations.ObjectivesThe aim of this study was to evaluate the US RA activity whether the ACPA were present or not.MethodsA cross-sectional study of patients followed-up for RA was conducted. Demographic, clinical and biological data were collected. RF and ACPA mesures were collected from medical records. We calculated the US-DAS28 in order to evaluate accurate activity of RA. All patients had an ultrasound (US) examination of 22 joints of hands (wrists, metacarpophalangeal, proximal interphalangeal). US was performed by an operator blinded to clinical and laboratory data. RA activity was evaluated by US-DAS28 by replacing swollen joints of the hands by joints expressing synovial hypertrophy or hyper vascularization in US.ResultsOne hundred and eighteen patients were enrolled, 83% were females. The mean age was 53 years-old. The mean duration of the disease was 11.6 months. The RF was positive in 64 (55%) patients and the ACPA was positive in 31 (26%) patients. The median DAS28 was 5,52 [2,91-7,81]. The medianUS-DAS28 was 5.29 [1.98- 7.83]. The comparison between US-DAS28 according to immunological status is showed in table 1.Table 1.US-DAS28 depending on RF and ACPA statusUS-DAS28pRF (+)5,290,90RF (−)5,26ACPA (+)5,310,80ACPA (−)5,29ConclusionsWe conclude that there was no significant difference of RA activity between seropositive or seronegative RA and also whether ACPA was positive or not. The analysis of bone damages should be compared in another study order to determinate the prognostic value of ACPA.ReferencesJung C, Jisuk B. Relation of rheumatoid factor and anti cyclic citrullined peptide antobody with disease activity in rheumatoid arthritis: cross sectional study. Rheumatol Int 2013.Disclosure of InterestNone declared
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.