Cardiac tamponade: an uncommon presenting feature of systemic lupus erythematosus, a case-based review

Chourabi, C.; Mahfoudhi, H.; Sayhi, S.; Dhahri, R.; Taamallah, Karima; Chenik, Sarra; Haggui, Abdeddayem; Hajlaoui, Nadhem; Lahidheb, Dhaker; Ajili, F.; Abdelhafidh, N. Ben; Louzir, B.; Fehri, Wafa

doi:10.11604/pamj.2020.36.368.25044

Cited by 6 publications

(8 citation statements)

References 10 publications

(10 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Pericardial effusion is often small and hemodynamically insignificant in SLE [4]. Despite the prevalence of pericarditis, cardiac tamponade is thought to affect less than 1% of SLE patients, making it a rare and uncommon condition [10,11]. It is a strikingly unusual occurrence as an initial manifestation of SLE.…”

Section: Discussionmentioning

confidence: 99%

“…The clinical manifestations of tamponade are brought on by a decrease in cardiac output and systemic venous congestion. Cardiac tamponade as the first sign of SLE is very rare and only limited to case reports and series [6,10,13,14]. Typical symptoms and signs include dyspnea, orthopnea, chest pain, pulsus paradoxus, jugular venous distension, and hypotension [3,7].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Cardiac Tamponade, an Unusual First Presentation of Systemic Lupus Erythematosus: A Case Report in a Rural Tertiary Hospital

Emorinken¹,

Dic-Ijiewere²,

Izirein³

2022

Cureus

View full text Add to dashboard Cite

Systemic lupus erythematosus (SLE) is a condition that manifests in a variety of ways. Although pericarditis and pericardial effusion are frequent cardiac manifestations of SLE, cardiac tamponade is rarely reported, especially as the initial manifestation of the disease. We describe a 38-year-old Nigerian lady who presented with three months of progressive dyspnea. She had intermittent fever, tachycardia, tachypnea, hypotension, jugular vein distension, and muffled heart sounds. Echocardiography confirmed cardiac tamponade. The ANA, anti-dsDNA, and anti-Sm antibodies were positive. She had a high ESR and low levels of blood complements. The diagnosis of SLE was established based on the 2019 EULAR/ACR classification criteria. She was treated with intravenous methylprednisolone, oral prednisolone, and hydroxychloroquine after undergoing an emergency echo-guided pericardiocentesis. She responded well to treatment, and she is currently being followed up on an outpatient basis. Clinicians should consider SLE as a differential when evaluating patients with pericardial effusion, as an accurate and timely diagnosis could be lifesaving.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Cardiac Tamponade, an Unusual First Presentation of Systemic Lupus Erythematosus: A Case Report in a Rural Tertiary Hospital

Emorinken¹,

Dic-Ijiewere²,

Izirein³

2022

Cureus

View full text Add to dashboard Cite

show abstract

“…When a genetically vulnerable person is exposed to environmental variables, a break in their tolerance results in the activation of their autoimmune system. The immune system is exposed to self-antigens as a result of cell damage brought on by infectious agents and other environmental variables [9]. This activation of T and B cells causes a persistent immunological response that is specifically directed against the damaged cells.…”

Section: Discussionmentioning

confidence: 99%

“…Heart-related issues will affect around half of SLE patients. The most common cardiac problems in SLE patients are pericarditis, myocarditis, valve issues, thrombosis, and anomalies of the conduction system [10]. Pericarditis, which has been associated with poor mortality, is the most frequent cardiac symptom of SLE.…”

Section: Discussionmentioning

confidence: 99%

“…Echocardiography is used to confirm the diagnosis. If feasible, have an echocardiogram done since it can grade and localize pericardial effusions, identify pericardial thickness, and spot intrapericardial adhesions in addition to being the gold standard for confirming cardiac tamponade [10]. The primary echocardiographic signs of pericardial tamponade include pericardial effusion, diastolic right ventricular collapse, systolic right atrial collapse, inferior vena cava plethora with little respiratory variation, and exaggerated respiratory cycle variation in mitral and tricuspid valve in-flow velocities [15].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Cardiac tamponade in a male as an initial presentation of SLE. An interesting case report

Affas¹

2022

J Clin Images Med Case Rep

View full text Add to dashboard Cite

A relapsing and remitting illness that may affect any organ system, systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory condition. Autoantibodies and immune complex development are its defining features. The heart is one of the organs that it might impact. In patients with SLE, the immune system’s response to dying cells is aberrant. The diagnosis of SLE is made on the basis of distinctive clinical findings in the skin, joints, kidneys, and central nervous system, as well as serological indicators like antinuclear antibodies (ANA), specifically antibodies to dsDNA. Nonsteroidal anti-inflammatory medicines (NSAIDs), corticosteroids, immunosuppressive medications, and biological agents may be used to treat lupus, depending on the symptoms, findings of blood tests, and the specific organs affected. Here we are reporting a rare case of a male with pericardial tamponade as a first symptom of SLE.

show abstract

Acute fibrinous constrictive pericarditis and large pericardial effusion as the first manifestation of systemic lupus erythematsous disease in an adult male patient

Yousefi‐Koma,

Jalalian,

Bagheri

2023

Clinical Case Reports

View full text Add to dashboard Cite

Key Clinical MessageSystemic lupus erythematosus (SLE) can have various manifestations. Although cardiac involvement is very common in SLE patients, a severe acute pericarditis as the first manifestation of SLE in a male patient is relatively rare. A 36‐year‐old male was admitted to our hospital with acute pericarditis, large circumferential fibrinous pericarditis, and major criteria of a high‐risk case of acute pericarditis. After a complete investigation, the underlying disease was revealed to be SLE. All of his symptoms were completely resolved after 6 weeks of treatment with non‐steroidal anti‐inflammatory drugs and corticosteroids with no need for a pericardiocentesis. Patients with acute fibrinous pericarditis should be considered and precisely investigated for multiorgan autoimmune process such as SLE, to avoid unnecessary intervention, and minimize the risk of recurrence and chronicity of the condition.

show abstract

Cardiac tamponade: an uncommon presenting feature of systemic lupus erythematosus, a case-based review

Cited by 6 publications

References 10 publications

Cardiac Tamponade, an Unusual First Presentation of Systemic Lupus Erythematosus: A Case Report in a Rural Tertiary Hospital

Cardiac Tamponade, an Unusual First Presentation of Systemic Lupus Erythematosus: A Case Report in a Rural Tertiary Hospital

Cardiac tamponade in a male as an initial presentation of SLE. An interesting case report

Acute fibrinous constrictive pericarditis and large pericardial effusion as the first manifestation of systemic lupus erythematsous disease in an adult male patient

Contact Info

Product

Resources

About