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A field experiment was conducted at Institute of Agriculture and Animal Science (IAAS), Bhairahawa during winter season of 2019/2020 to find out the performance of wheat genotypes under timely sown (November 29, 2019) and late sown (December 25, 2019) conditions. The research was carried out in two environments (timely sown and late sown) following alpha lattice design with two replications. Each replication consists of five blocks with four plots in each block. The results revealed that all genotypes performance was decreased in late sowing environment. In late sown condition, there was significant difference among genotypes for all the traits under study and under timely sown condition, there was significant difference among genotype for all traits under study except weight of grains per spike and grain yield. The maximum yield was recorded in NL 1179 and Bhirkuti in timely and late sown conditions respectively. It was found that the mean grain yield in timely sown condition is 90.77 % higher than in late sown condition. The maximum grain yield was recorded in NL 1179 across combine environment. Int. J. Appl. Sci. Biotechnol. Vol 8(2): 161-169

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Glandular odontogenic cyst is a rare developmental odontogenic cyst that bears similarity to several other odontogenic lesions. Till 2017, only 169 such cases have been reported in the literature. Herein, we describe one more case of it occurring in a 35‐year‐old female patient.

Assessment of variability and traits association in crop help to enhance selection efficiency. Therefore, the present investigation entitled “Variability, Correlation and Path Coefficient Analysis for Agro-morphological Traits in Wheat Genotypes (Triticum aestivum L.) under Normal and Heat Stress Conditions” was carried out during winterseason of 2019/2020 at Institute of Agriculture and Animal Science (IAAS), Bhairahawa, Nepal to identify traits that highly contribute to grain yield and suitable for its further improvement. The experiment was laid out following alpha lattice design with two replications. The twentygenotypes of wheat was sown in two different environments viz., irrigated and heat stress in November 29, 2019 and December 25, 2019 respectively. It was found that under normal condition, moderate GCV and PCV were recorded in SW, TGW, NGPS, and WGPS. Under heat stress condition, high GCV and PCV were observed in GY. High heritability and high GAM was observed in TGW & GY, NGPS, WGPS, TGW under normal and heat stress condition respectively. Under normal condition SW exhibited positive correlation and high positive direct effect on GY at genetic level and WGPS at phenotypic level. And under heat stress condition SW exhibited positive correlation and high positive direct effect on GY. Whereas, at phenotypic level, WGPS and PH exhibited high positive direct effect on grain yield. Hence it is clear that spike weight and weight of grains per spike are important traits for grain yield improvement. Int. J. Appl. Sci. Biotechnol. Vol 9(1): 65-74

Introduction: The incidence of oral cancer is rising due to overindulgence in tobacco chewing and smoking. Its detection in early stage makes it more amenable to treatment and helps to reduce associated morbidity. However, most cases are diagnosed at later stage due to lack of awareness about oral cancer and associated risk factors. This study aims to observe the oral cancer awareness among undergraduate dental students and dental surgeons of three dental institutions of Nepal. Methods: This descriptive cross-sectional study was conducted in three dental institutions of Nepal from January 2019 to May 2019. Convenience sampling method was used. The data was collected from 508 participants through questionnaire adopted from Carter and Ogden. Point estimate at 95 % Confidence Interval was calculated along with frequency and proportion for binary data. Statistical analysis was done using Statistical Package for the Social Sciences. Results: Our study showed that 120 (23.6%) of the participants were well informed about the clinical appearance of oral cancer at 95% confidence interval (19.91-27.29). Most of the participants i.e. 457 (89.96%) and 395 (77.75%) were aware that smoking and chewing tobacco were most commonly recognized risk factors. Only 200 (39.37%) participants were aware that non-healing ulcer is considered as the changes associated with oral cancer. Three hundred and forty-four (67.7%) said they have no knowledge about the prevention and detection of oral cancer. Conclusions: Our study exhibited the apparent lack of awareness in some aspects of oral cancer and highlights the need of enhancing the undergraduate dental syllabus.

This review provides a comprehensive overview of the basic and applied aspects of different plant growth regulators in the regulation of growth and development of cucumber plants. The study is completely based on the use of secondary sources of data; related journals, government institutes, and relevant reports. Foliar application of PGRs has been shown to change the physiological and developmental processes, including plant vegetative growth, sex expression, yield, and yield components in cucumber. There are basically two types of growth regulators; plant growth promoters such as auxin, gibberellins, cytokinins, maleic hydrazide, ethephon, etc. and plant growth inhibitors such as ethylene, abscisic acids, dormins, etc. The combined use of auxins and gibberellins result in increased secondary growth. Maleic hydrazide (MH) along with Ethephon at 100 ppm each increases the number of nodes and primary branches.  Ethrel at 300-400 ppm retards the secondary development and increase femaleness, and at 200-300 ppm make fruit surface smooth. Silver nitrate (AgNO3) at 400 ppm enhances the maleness in cucumber. Application of Ethephon at 300 ppm reduces the harvesting time of the fruit. Salicylic acid (at 2 doses of 0.07 mm/l + 0.18 mm/l) increases chlorophyll content and its exogenous application increases the fruit yield. Maleic Hydrazide (MH) alone at 100 ppm increases the femaleness, inhibits apical growth at 50-100 ppm, and increases fruit size at 200 ppm. Therefore, various auxin [indole-3-acetic acid (IAA), NAA], auxin transport inhibitor (TIBA), cytokinins (KIN), gibberellin [gibberellic acid (GA3)], ABA, ethylene [(2-chloroethylphosphonic acid (ethrel; ethephon; CEPA)] and growth retardant (MH) have been applied to control the vegetative growth and to maximize yield of cucumber. Numerous obstacles have hindered the quality cucumber production in Nepal; like environmental stresses, biotic and abiotic constraints, pest and disease outbreaks, and many others. The use of exogenous plant growth regulators has been crucial to Nepali cucumber producers as plant growth regulators has hasty effect on vegetative as well as the quality yield of plants. This study aims to reveal the suitable concentrations for the applications of growth regulators so that the use of such regulators is environmentally and toxicologically safe for both plants and the consumers.

Tuberculosis is a common infection caused by Mycobacterium tuberculosis. Tuberculosis can affect many organ systems of the human body including the gastrointestinal tract. Esophageal involvement of tuberculosis is however rare.A 60 years old male from Nepal with an occupational history suggestive of exposure to tuberculosis presented with dysphagia. He did not have any other complaints and his physical examination was unremarkable. An upper gastrointestinal endoscopic examination revealed an esophageal ulcer at 25 cm from incisors. Biopsy from the edge of the ulcer revealed granulomas with central caseous necrosis. A computed tomography scan of the chest and abdomen did not reveal additional lesions. Considering the higher prevalence of tuberculosis in the geographical area, he was started on an empirical antitubercular regimen. His dysphagia subsided within two weeks of starting therapy. A repeat upper gastrointestinal examination at six months of therapy revealed complete healing of the esophageal lesion.In this case report, we review the symptomatology, diagnosis, and treatment of esophageal tuberculosis.