Primary Esophageal Tuberculosis With Dysphagia

Paudel, Mukesh S; Parajuli, Sandesh; Baral, Bidisha; Poudel, Pratibha; Dhungana, Ishan

doi:10.7759/cureus.16236

Cited by 3 publications

(7 citation statements)

References 14 publications

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“…The analysis indicated that all the traits are highly co-related with each other. No significant correlation was found previously between these traits (Ram Poudel et al, 2021). Under HS, RL and RW were significantly correlated to SL and SW.…”

Section: Hsi Of Historical Wheat Cultivarscontrasting

confidence: 57%

Genome-wide association for heat tolerance at seedling stage in historical spring wheat cultivars

et al. 2022

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Increasing global temperature has adverse effects on crop health and productivity at both seedling and reproductivity stages. It is paramount to develop heat tolerant wheat cultivars able to sustain under high and fluctuating temperature conditions. An experiment was conducted to characterize 194 historical wheat cultivars of Pakistan under high temperature at seedling stage to identify loci associated with heat tolerance using genome-wide association studies (GWAS). A quantitative trait locus, TaHST1, on chr4A was also characterized to identify the haplotypes at this locus associated with heat tolerance in wheat from Pakistan. Initially, the diversity panel was planted under control conditions (25°C/20°C day and night temperature) in a glass house. At three leaf stage, plants were subjected to heat stress (HS) by increasing temperature (40°C/35°C day and night), while one treatment was kept at control condition. After 7 days of HS, data were collected for seedling morphology. Heat stress reduced these traits by 25% (root weight) to 40% (shoot weight), and shoot biomass was largely affected by heat stress. A GWAS model, fixed and random model circulating probability unification (FarmCPU), identified 43 quantitative trait nucleotides (QTNs) on all chromosomes, except chr7B, were associated under both HS and control conditions. Thirteen QTNs were identified in control, while 30 QTNs were identified in HS condition. In total, 24 haplotypes were identified at TaHST1 locus, and most of the heat tolerant genotypes were assigned to Hap-20 and Hap-21. Eleven QTNs were identified within 0.3–3.1 Mb proximity of heat shock protein (HSP). Conclusively, this study provided a detailed genetic framework of heat tolerance in wheat at the seedling stage and identify potential genetic regions associated with heat tolerance which can be used for marker assisted selection (MAS) in breeding for heat stress tolerance.

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Section: Hsi Of Historical Wheat Cultivarscontrasting

confidence: 57%

Genome-wide association for heat tolerance at seedling stage in historical spring wheat cultivars

et al. 2022

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“…TB of the esophagus often affects its middle section [6]. TB of the esophagus typically results from direct extension from surrounding structures, such as mediastinal lymph nodes and pulmonary sites [2]. It is hypothesized that the accumulation of swallowed sputum or infected milk products is one of the reasons for GI TB [7].…”

Section: Discussionmentioning

confidence: 99%

“…According to recent studies, tuberculosis (TB) is the largest cause of death worldwide from a single infectious disease agent [ 1 ]. In 2019, around 10 million people contracted tuberculosis worldwide, and an estimated 1.2 million HIV-negative people died from TB [ 2 ]. It affects the respiratory system predominately.…”

Section: Introductionmentioning

confidence: 99%

“…It affects the respiratory system predominately. Eleven percent of individuals with extrapulmonary TB had gastrointestinal (GI) involvement [ 2 ], with the terminal ileum, cecum, and peritoneum being the most common sites [ 3 ]. TB affecting the esophagus is one of the rarest forms of extrapulmonary TB, with a frequency of 0.2% [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

“…Eleven percent of individuals with extrapulmonary TB had gastrointestinal (GI) involvement [ 2 ], with the terminal ileum, cecum, and peritoneum being the most common sites [ 3 ]. TB affecting the esophagus is one of the rarest forms of extrapulmonary TB, with a frequency of 0.2% [ 2 ]. Nonetheless, claims of esophageal tuberculosis (ET) have grown during the previous two decades.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

An Unusual Presentation of Esophageal Tuberculosis: A Case Report

Zahra¹,

Ravikumar²,

Voloshyna³

et al. 2022

Cureus

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The lungs, kidneys, liver, and pancreas are just some of the organs that can be affected by tuberculosis.Tuberculosis is a disease that can affect many organs of the human body. Rarely can tuberculosis (TB) manifest itself in the digestive tract; in fact, the gastrointestinal tract ranks as the sixth most common site of extrapulmonary TB. However, involvement of the esophagus by tuberculosis is extremely uncommon. We present a case of esophageal tuberculosis in a 27-year-old man with epigastric pain and weight loss as his only symptoms. There were no complaints of odynophagia or dysphagia, nor was there any evidence of immunodeficiency. Upper gastrointestinal endoscopy found an ulcer 26 centimeters from the incisor. Histopathology and a biopsy confirmed the diagnosis of primary esophageal tuberculosis. Six months after beginning anti-TB therapy, he was confirmed to be free of tuberculosis.

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Comments and Illustrations of Ultrasound Findings in Extrapulmonary Tuberculosis Manifestations

Möller,

Löwe,

Jenssen

et al. 2024

Diagnostics

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This review describes the appearance of extrapulmonary tuberculosis manifestations in comprehensive and multiparametric ultrasound imaging. The aim is to increase awareness of typical ultrasound findings regarding extrapulmonary tuberculosis, correlate those with pathological features, and facilitate differential diagnosis. Point of care ultrasound protocols can be used as a screening method in high-risk populations, although the negative findings do not exclude tuberculosis. Conversely, the diagnosis of extrapulmonary tuberculosis can never be made using ultrasound alone, as many ultrasound findings in extrapulmonary tuberculosis are non-specific. However, ultrasound-based sampling techniques can significantly facilitate the collection of samples for microbiological or molecular proof of tuberculosis, as well as facilitating the establishment of alternative diagnoses.

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Primary Esophageal Tuberculosis With Dysphagia

Cited by 3 publications

References 14 publications

Genome-wide association for heat tolerance at seedling stage in historical spring wheat cultivars

Genome-wide association for heat tolerance at seedling stage in historical spring wheat cultivars

An Unusual Presentation of Esophageal Tuberculosis: A Case Report

Comments and Illustrations of Ultrasound Findings in Extrapulmonary Tuberculosis Manifestations

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