Sunscreen ingredient such as sulisobenzone (SBZ) has the tendency to degrade when exposed to UV-radiation which becomes major problem for their further development and application in cosmetic industry. Host-guest inclusion...
Our present study
intended to investigate the encapsulation of
DL-AGT within the lipophilic cavity of a β-CD molecule. The
consequential inclusion system was characterized by UV–visible
spectroscopy and
1
H NMR, PXRD, SEM, and FT-IR studies.
Molecular docking was performed for the inclusion complex to discover
the most proper orientation, and it was seen that the drug DL-AGT
fits into the cavity of β-CD in a 1:1 ratio, which was also
confirmed from the Job plot. Furthermore, a comparison was done on
the basis of cell viability between the drug and its inclusion complex.
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