20.000/mm³ and requirements of renal replacement therapy (p <0.05). Twelve percent of patients evolved to chronic renal failure and the risk factors during the acute phase were the need for renal replacement therapy, anuria, WCC >20.000/mm³, seizures and hypertension. Conclusions: The present study emphasizes important clinical and epidemiological aspeets ofHUSin a Chilean pediatricpopulation.]]>
Given that childhood obesity is an epidemic, the frequency of critically-ill patients who are overweight or obese seen at intensive care units has increased rapidly. Adipose tissue is an endocrine organ that secretes a number of protein hormones, including leptin, which stands out because it regulates adipose tissue mass. The presence of arterial hypertension, metabolic syndrome, diabetes mellitus, respiratory disease and chronic kidney disease may become apparent and complicate the course of obese pediatric patients in the Intensive Care Unit. Obesity management is complex and should involve patients, their families and the medical community. It should be coordinated with comprehensive government health policies and implemented in conjunction with a change in cultural context
El desarrollo de un síndrome nefrótico en concomitancia con una tiroiditis de Hashimoto es una asociación infrecuente en la edad pediátrica. Objetivo: Reportar una complicación infrecuente de la tiroiditis autoinmune, como es la aparición de un síndrome nefrótico. Caso Clínico: Paciente de 10 años que se presenta con síndrome nefrótico y bocio. Se pesquisa antecedente de tiroiditis autoinmune e hipotiroidismo no tratado. Se inicia terapia corticoidal y hormonal de sustitución (levotiroxina), logrando buena respuesta clínica y de laboratorio. Conclusión: La tiroiditis autoinmune impacta en la fisiología renal a través de mecanismos inmunológicos y no inmunológicos. Paralelamente, la repercusión renal puede afectar la función tiroidea. La importancia de la presente comunicación radica en reportar una complicación infrecuente de la tiroiditis autoinmune, como lo es la aparición de síndrome nefrótico.
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