The purpose of this paper is to give an overview of the recent surgical intraoperational applications of indocyanine green fluorescence imaging methods, the basics of the technology, and instrumentation used. Well over 200 papers describing this technique in clinical setting are reviewed. In addition to the surgical applications, other recent medical applications of ICG are briefly examined.
More and more satellites are populating the sky nowadays in the Low Earth orbits (LEO). Most of the targeted applications are related to broadband and narrowband communications, Earth observation, synthetic aperture radar, and internet-of-Things (IoT) connectivity. In addition to these targeted applications, there is yet-to-be-harnessed potential for LEO and positioning, navigation, and timing (PNT) systems, or what is nowadays referred to as LEO-PNT. No commercial LEO-PNT solutions currently exist and there is no unified research on LEO-PNT concepts. Our survey aims to fill the gaps in knowledge regarding what a LEO-PNT system entails, its technical design steps and challenges, what physical layer parameters are viable solutions, what tools can be used for a LEO-PNT design (e.g., optimisation steps, hardware and software simulators, etc.), the existing models of wireless channels for satellite-toground and ground-to-satellite propagation, and the commercial prospects of a future LEO-PNT system. A comprehensive and multidisciplinary survey is provided by a team of authors with complementary expertise in wireless communications, signal processing, navigation and tracking, physics, machine learning, Earth observation, remote sensing, digital economy, and business models.
Logistics is an important driver for the competitiveness of industries and material supply. The development of smart logistics, powered by precise positioning and communication technologies can significantly improve the efficiency of logistics. The emerging technology of ultra-wideband (UWB) precision positioning has attracted significant attention throughout the previous decade owing to its promising capabilities over other radio frequency-based indoor localisation systems. In addition, UWB is characterised by large bandwidth and data rate, short message length, low transmission power and high penetration capability, which are all favourable for indoor positioning applications. However, UWB localisation technology faces several challenges that are somewhat similar to other technologies, such as mitigating errors that originate from non-line-of-sight (NLOS) situations and tackling signal interference in dense environments, and when required to operate in extreme conditions. This paper reviews the most recent advances made in UWB positioning systems over the last five years, with a focus on high-ranking articles. In addition to going through more conventional solutions to UWB challenges, modern solutions, which involve the use of machine learning and sensor data fusion, are discussed. We highlight the most promising findings of the recently implemented and foreseen UWB positioning systems by providing a summary of each reviewed article. Additionally, we address a major challenge that faces the UWB positioning technology: NLOS situations, focusing on some proposed remedies such as multi-sensor fusion and machine learning. As an application, this study introduces how UWB technology promotes smart logistics by offering indoor positioning to improve efficiencies in the delivery of goods from the source to the customer. Furthermore, it demonstrates the benefits of UWB technology for accurate positioning and tracking of both stationary and moving items, and machinery in an indoor logistics environment.
Scar hypertrophy is a significant clinical problem involving both linear scars from elective surgery and scars caused by trauma or burns. The treatment of hypertrophic scars is often time consuming, and patients may need to be followed up for months or even years. The methods for reliable quantification of scar hypertrophy are at present unsatisfying. We have developed a new, objective method, Spectrocutometry, for documentation and quantification of scar hypertrophy. The instrument is based on standardized digital imaging and spectral modeling and calculates the estimated concentration change of hemoglobin and melanin from the entire scar and also provides standardized images for documentation. Three plastic surgeons have assessed 37 scars from melanoma surgery using Spectrocutometry, the Vancouver scar scale, and the patient and observer scar assessment scale. The intraclass correlation coefficient for the Vancouver scar scale and the patient and observer scar assessment scale was lower than required for reliable assessment (r=0.66 and 0.60, respectively). The intraclass correlation coefficient for Spectrocutometry was high (r=0.89 and 0.88). A Bayesian network analysis revealed a strong dependency between the estimated concentration change of hemoglobin and scar pain. Spectrocutometry is a feasible method for measuring scar hypertrophy. It is shown to be more reliable than subjective rating in assessing linear surgical scars.
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