Objectives: To determine the attitude of general practitioners towards evidence based medicine and their related educational needs. Design: A questionnaire study of general practitioners. Setting: General practice in the former Wessex region, England.

The reduced tidal volume strategy used in this study was safe. Failure to observe beneficial effects of small tidal volume ventilation treatment in important clinical outcome variables may have occurred because a) the sample size was too small to discern small treatment effects; b) the differences in tidal volumes and plateau pressures were modest; or c) reduced tidal volume ventilation is not beneficial.

We report a disease-specific multivariable logistic regression model to estimate the probability of hospital mortality in a cohort of critically ill cancer patients admitted to the ICU. The model consists of 16 unambiguous and readily available variables. This model should move the discussion regarding appropriate use of ICU resources forward. Additional validation in a community hospital setting is warranted.

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This model can be used to estimate the probability of hospital survival for classes of adult cancer patients who require mechanical ventilation and can help to guide physicians, patients, and families in deciding goals and direction of treatment. Prospective independent validation in different medical settings is warranted.

Summary:idiopathic noninfectious pneumonia; (3) pulmonary edema (hydrostatic or noncardiogenic); (4) respiratory failure (pulmonary and extrapulmonary etiologies); (5) inflammaFiberoptic bronchoscopy (FOB) has been reported to have a high diagnostic yield and to be safe in BMT tory conditions (diffuse alveolar damage (DAD), bronchiolitis obliterans organizing pneumonia (BOOP), bronchiolitis patients with pulmonary infiltrates. At our institution, BMT patients with respiratory symptoms and/or pulobliterans (BO), and pulmonary graft-versus-host disease); (6) pulmonary hemorrhage; and (7) The use of FOB to evaluate pulmonary infiltrates in BMT patients was not previously standardized at our institution. (15%) occurred in 10 FOBs (five acute respiratory failure, three pneumothoraces, one nose bleed, one death).Although the medical literature indicates that FOB in BMT patients with pulmonary infiltrates is a safe and valuable Hospital and 6-month survival based on episodes of clinical pneumonia were 47 and 32%, respectively. diagnostic procedure, its impact on providing a diagnosis, guiding treatment, and patient outcome at our institution Patients who had a diagnostic FOB or a FOB that changed treatment did not have better hospital or 6-was unclear. A data base was established to collect existing clinical information to assess the yield, impact on treatmonth survival compared to patients who had FOBs that were nondiagnostic or did not change treatment.ment, safety and survival in BMT patients who had FOB to evaluate respiratory symptoms and/or pulmonary infiltrates. FOB in our BMT patient population, had a low diagnostic yield (31%), infrequently changed treatment (24%), a significant complication rate (15%) and was not associated with improved patient survival. The role of rouMaterials and methods tine diagnostic FOB in BMT patients with pulmonary infiltrates and/or respiratory symptoms should be rePatient population evaluated.

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