Utility of On-Site Cytopathology Assessment for Bronchoscopic Evaluation of Lung Masses and Adenopathy

Flexible Bronchoscopy in the Evaluation of Mediastinal and Hilar Lymphadenopathy

“…CT guidance can increase its sensitivity and specificity [18]. As per Diette et al [19], the availability of rapid on site evaluation of samples by a cytopathologist improved the diagnostic yield when sampling hilar and mediastinal lymphadenopathy. Endoscopic ultrasound-guided fine needle aspiration has shown to improve the results [20].…”

Should transbronchial needle aspiration and rapid on-site cytologic evaluation be performed before mediastinoscopy? “Analysis of 239 cases”

“…[1,2] However, the diagnostic yield of TBNA varies widely in reported series, ranging from 20 to 90%. [1,3] Diagnostic yield of neoplasms can be improved with rapid on-site cytologic evaluation (ROSE) by a cytopathologist or endobronchial ultrasound (EBUS).…”

“…[1,3] Diagnostic yield of neoplasms can be improved with rapid on-site cytologic evaluation (ROSE) by a cytopathologist or endobronchial ultrasound (EBUS). [1,2,4] Transbronchial needle aspiration and rapid on-site cytologic evaluation can reduce risk, costs, morbidity, and anxiety for patients, as well as the time to definitive treatments. [1][2][3][4][5] Surgical resection is considered as the best treatment method in NSCLC; however, clinical evidence indicates that patients with mediastinal lymph node (MLN) metastasis have poor prognosis.…”

“…[1,2,4] Transbronchial needle aspiration and rapid on-site cytologic evaluation can reduce risk, costs, morbidity, and anxiety for patients, as well as the time to definitive treatments. [1][2][3][4][5] Surgical resection is considered as the best treatment method in NSCLC; however, clinical evidence indicates that patients with mediastinal lymph node (MLN) metastasis have poor prognosis. [2,3] Therefore, accurate MLN staging is critical for selecting patients suitable for surgery.…”

“…[1][2][3][4][5] Surgical resection is considered as the best treatment method in NSCLC; however, clinical evidence indicates that patients with mediastinal lymph node (MLN) metastasis have poor prognosis. [2,3] Therefore, accurate MLN staging is critical for selecting patients suitable for surgery. [4] Mediastinoscopy remains the gold standard for mediastinal staging of NSCLC, but this procedure is associated with certain complications, such as bleeding, recurrent nerve damage, and thoracic duct injury.…”