The development of high-performance nanocarriers for nutraceuticals or drugs has become one of the topical research subjects in the functional food fields. In this work, we for the first time propose a novel and ecofriendly process to obtain a kind of nanostructured soy β-conglycinin (β-CG; a major soy storage globulin) as outstanding nanocarriers for poorly soluble bioactives (e.g., curcumin), by a urea-assisted disassembly and reassembly strategy. At urea concentrations > 4 M, the structure of β-CG gradually dissociated into its separate subunits (α, α′, and β) and even denatured (depending on the type of subunits); after dialysis to remove urea, the dissociated subunits would reassemble into a kind of core−shell nanostructured particles, in which aggregated β-subunits acted as the core while the shell layer was mainly composed of αand α′-subunits. The core−shell nanoparticles were favorably formed at protein concentrations of 1.0−2.0 wt %. Curcumin crystals were directly introduced into the β-CG solution at high urea concentrations (e.g., 8 M) and would preferentially interact with the denatured β-subunits. As a consequence, almost all of the curcumin molecules were encapsulated in the core part of the reassembled core− shell nanoparticles. The loading amount of curcumin in these nanoparticles could reach 18 g of curcumin per 100 g of protein, which far exceeds those reported previously. The encapsulated curcumin exhibited a high water solubility, extraordinary thermal stability, and improved bioaccessibility, as well as a sustained release behavior. The findings provide a novel strategy to fabricate a kind of high-encapsulation-performance, organic solvent-free, and biocompatible nanocarrier for hydrophobic nutraceuticals and drugs.
Since solid particles suspended in the fluid can cause wear in centrifugal pumps, intensive attention has been focused on the numerical prediction for the wear of flow parts in centrifugal pumps. However, most numerical studies have focused on only one wear model and a sphere particle model. The impact of particle shape on the wear of flow parts in centrifugal pumps is under-studied, particularly considering abrasive and impact wear simultaneously. In this work, the Computational Fluid Dynamics (CFD)-Discrete Element Method (DEM) coupling method with an abrasive and impact wear prediction model was adopted to study the wear characteristics of a centrifugal pump. Moreover, four regular polyhedron particles and a sphere particle with the same equivalent diameter but different sphericity were mainly analyzed. The results demonstrate that more particles move closer to the blade pressure side in the impeller passage, and particles tend to cluster in specific areas within the volute as sphericity increases. The volute suffers the principal wear erosion no matter what the shapes of particles and wear model are. Both the impact and abrasive wear within the impeller occur primarily on the blade leading edge. The pump’s overall impact wear rate decreases first and then increases with particle sphericity rising, while the pump’s overall abrasive wear rate grows steadily.
Passive grinding is a new rail grinding strategy. In this work, the influence of grinding pressure on the removal behaviors of rail material in passive grinding was investigated by using a self-designed passive grinding simulator. Meanwhile, the surface morphology of the rail and grinding wheel were observed, and the grinding force and temperature were measured during the experiment. Results show that the increase of grinding pressure leads to the rise of rail removal rate, i.e., grinding efficiency, surface roughness, residual stress, grinding force and grinding temperature. Inversely, the enhancement of grinding pressure and grinding force will reduce the grinding ratio, which indicates that service life of grinding wheel decreases. The debris presents dissimilar morphology under different grinding pressure, which reflects the distinction in grinding process. Therefore, for rail passive grinding, the appropriate grinding pressure should be selected to balance the grinding quality and the use of grinding wheel.
Passive grinding is a high-speed rail grinding maintenance strategy, which is completely different from the conventional rail active grinding system. In contrast to active grinding, there is no power to drive the grinding wheel to rotate actively in passive grinding. The passive grinding process is realized only by the cooperation of grinding pressure, relative motion, and deflection angle. Grinding tests for passive grinding can help to improve the passive grinding process specifications and be used for the development of passive grinding wheels. However, most of the known grinding methods are active grinding, while the passive grinding machines and processes are rarely studied. Therefore, a passive grinding test machine was designed to simulate passive grinding in this study. This paper gives a detailed description and explanation of the structure and function of the passive grinding tester. Moreover, the characteristics of the grinding process and parameter settings of the testing machine were discussed based on the passive grinding principle. The design of a passive grinding test machine provides experimental equipment support for investigating passive grinding behavior and grinding process.
High-speed rail grinding is a unique passive grinding maintenance strategy that differs from conventional grinding techniques. Its grinding behavior is dependent on the relative motion between the grinding wheel and rail; hence, it possesses great speed and efficiency. In this study, the effects of the duration of grinding time and the increase in the number of grinding passes on the grinding of high-speed rails were investigated using passive grinding tests with a single grinding time of 10 s and 30 s and grinding passes of once, twice, and three times, respectively. The results show that when the total grinding time was the same, the rail removal, grinding ratio of grinding wheels, rail grinding effect, grinding force, and grinding temperature were better in three passes of 10 s grinding than in one pass of 30 s grinding, indicating that the short-time and multi-pass grinding scheme is not only conducive to improving the grinding efficiency and grinding quality in the high-speed rail grinding but can also extend the service life of the grinding wheels. Moreover, when the single grinding times were 10 s and 30 s, respectively, the grinding removal, grinding efficiency, grinding marks depth, and surface roughness of rail increased with the number of grinding passes, implying that the desired rail grinding objective can be achieved by extending the grinding time via the multi-pass grinding strategy. The results and theoretical analysis of this study will contribute to re-conceptualizing the practical operation of high-speed rail grinding and provide references for the development of the grinding process and grinding technology.
A scheme for manufacturing heavy-duty rail grinding wheels with silicone-modified phenolic resin (SMPR) as a binder in the field of rail grinding is presented to improve the performance of grinding wheels. To optimize the heat resistance and mechanical performance of rail grinding wheels, an SMPR for industrial production of rail grinding wheels was prepared in a two-step reaction using methyl-trimethoxy-silane (MTMS) as the organosilicon modifier by guiding the occurrence of the transesterification and addition polymerization reactions. The effect of MTMS concentration on the performance of silicone-modified phenolic resin for application in rail grinding wheels was investigated. The molecular structure, thermal stability, bending strength, and impact strength values of the SMPR were characterized by Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), and mechanical property testing, and the effect of MTMS content on the resin properties was investigated. The results indicated that MTMS successfully improved the performance of the phenolic resin. The thermogravimetric weight loss temperature of the SMPR modified by MTMS with 40% phenol mass at 30% weight loss is 66% higher than that of common phenolic resin (UMPR), exhibiting the best thermal stability; in addition, its bending strength and impact strength were enhanced by approximately 14% and 6%, respectively, compared with those of common UMPR. This study utilized an innovative Bronsted acid as a catalyst and simplified several intermediate reactions in the conventional silicone-modified phenolic resin technology. This new investigation of the synthesis process decreases the manufacturing cost of the SMPR, liberates it from the restrictions of grinding applications, and enables the SMPR to maximize its performance in the rail grinding industry. This study serves as a reference for future work on resin binders for grinding wheels and the development of rail grinding wheel manufacturing technology.
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