WRVD is a situation that frequently is listed as a reason for work absenteeism, functional rehabilitation, or for prolonged absence from work. Currently, forensic physicians have no comparative parameters to help with the analysis of vocal disorders. In certain situations WRVD may cause, work disability. This disorder may be labor-related, or be an adjuvant factor to work-related diseases.

several adjuvant therapies to surgery have been used to modulate the healing process of vocal folds, including topic mitomycin (MTC). Aim: to evaluate the effect of topical MTC in the healing process of vocal folds 30 days after the exeresis of a mucosal fragment with CO 2 laser in a swine model (control group without mitomycin and study group with topical MTC), with collagen deposition measurement. Study type: prospective experimental in swine. Methods: two groups of 6 swine each were subjected to exeresis of a mucosal fragment of the vocal fold with CO 2 laser. Immediately after the procedure MTC was applied topically for three minutes on the study group. Thirty days later the animals were slaughtered and samples of the vocal folds were collected for histological analysis, with the purpose of quantifying collagen deposition by Picrosirius Red stain. Results: the average area of total collagen in the vocal folds in the control group was 2.648,03 µm2, whereas in the study group it was 2.200,30 µm2 (p = 0.0043). Conclusion: topical application of MTC after the exeresis of a mucous fragment of vocal fold with CO 2 laser in swine significantly decreased total collagen deposition.

Purpose:To evaluate the influence of hypothyroidism in tracheal wound healing process. Methods: A controlled study was designed with 48 male Wistar rats, divided into two groups: study and control groups. In the first one hypothyroidism was surgically induced and 10 weeks after, a tracheal opening followed by suture was performed in both groups, subdivided into 7, 14, and 21 days in accordance with the date of animals death. A laboratorial evaluation was performed to prove the decreased in thyroid function in the study group. Also a macroscopic evaluation through a stablished protocol and a microscopic analysis with Hematoxylin-eosin and Sirius-Red staining methods were done. Results: The laboratorial evaluation certified suppressed thyroid function in the study group. The macroscopic evaluation showed the presence of suture blockade in the study group in all the evaluated days. Microscopic analysis showed a prolongated inflammatory process and less collagen with delay in organization in the study group comparing to control group. All these data were statistic significant. Conclusion: Hypothyroidism had an influence in tracheal wound healing process, promoting delay in the inflammatory and organization processes and diminished tissue collagen quantity. Key words: Wound Healing. Hypothyroidism. Trachea. Rats. RESUMOObjetivo: Investigar a influência que o hipotireoidismo exerce no processo cicatricial da traquéia. Métodos: Estudo controlado, com 48 ratos Wistar machos, divididos em dois grupos, denominados: grupo estudo e grupo controle. No primeiro induziu-se hipotireoidismo cirurgicamente e após 10 semanas, realizou-se nos dois grupos o procedimento de abertura traqueal seguida de sutura. Houve subdivisão destes grupos em 7, 14 e 21 dias, de acordo com a data de morte dos animais. Foi realizada avaliação laboratorial para comprovar o hipotireoidismo no grupo estudo, avaliação macroscópica e microscópica através das colorações de hematoxilina-eosina e Sirius Red. Resultados: A avaliação laboratorial atestou que o grupo estudo encontrava-se em estado de hipotireoidismo. A avaliação macroscópica demonstrou predomínio de bloqueio da sutura no grupo estudo em todos os momentos avaliados. A microscopia comprovou prolongamento da fase inflamatória e diminuição da quantidade total de colágeno bem como atraso na sua organização no grupo estudo em relação ao grupo controle. Todos estes dados apresentaram significância estatística. Conclusão: O hipotireoidismo influencia no processo de cicatrização traqueal prolongando a fase inflamatória, diminuindo a quantidade de colágeno e atrasando sua maturação e organização. Descritores: Cicatrização de Feridas. Hipotireoidismo. Traquéia. Ratos.

topical application of MTC after the exeresis of a mucous fragment of vocal fold with CO2 laser in swine significantly decreased total collagen deposition.

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Motors and handpieces with the piezoelectric system have recently been used in several surgeries, following the current minimally invasive trend surgery. The system consists of crystals or ceramics undergoing deformation when exposed to electrical current, resulting in an oscillating movement with ultrasound frequency. In the Oral and Maxillofacial Surgery field activity, the piezosurgery may be used in maxillary and mandibular osteotomies in the orthognathic surgery, alveolar corticotomies, cysts tumors, facial trauma surgery, among others. This study aims to present a literary review on the piezoelectric system, which allows discussion to their use and effectiveness in oral surgery procedures.

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