How does peer teaching compare to faculty teaching? A systematic review and meta-analysis Abstract PurposeIn undergraduate medical education, peer-teaching has become an established and common method to enhance student learning. Evidence suggests peer-teaching provides learning benefits for both learners and tutors.We aimed to describe the outcomes for medical students taught by peers through systematic review and meta-analysis of existing literature. MethodsSeven databases were searched through 21 terms and their Boolean combinations. Studies reporting knowledge or skills outcomes of students taught by peers compared to those taught by faculty or qualified clinicians were included.Extracted data on students' knowledge and skills outcomes were synthesised through a random effects model meta-analysis. Results Peer Teaching versus Faculty Teaching v6.0 2The search yielded 2,292 studies. 553 duplicates and 1,611 irrelevant articles were removed during title-screening. The abstracts of 128 papers were screened against the inclusion and exclusion criteria. Ten studies have been included in the review.Meta-analyses showed no significant difference in peer-teaching compared to faculty teaching for knowledge or skills outcomes, standardised mean differences were 0.07 (95% CI: -0.07, 0.21) and 0.11 (95% CI: -0.07, 1.29) respectively. ConclusionStudents taught by peers do not have significantly different outcomes to those taught by faculty. As the process of teaching helps to develop both tutor knowledge and teaching skills, peer-teaching should be supported.Peer Teaching versus Faculty Teaching v6.0
BackgroundPrevention guidelines for infants at high risk of allergic disease recommend hydrolysed formula if formula is introduced before 6 months, but evidence is mixed. Adding specific oligosaccharides may improve outcomes.ObjectiveTo evaluate whether partially hydrolysed whey formula containing oligosaccharides (0.8 g/100 ml) (pHF‐OS) can prevent eczema in high‐risk infants [ISRCTN65195597].MethodsWe conducted a parallel‐group, multicentre, randomized double‐blind controlled trial of pHF‐OS vs standard cow's milk formula. Infants with a family history of allergic disease were randomized (stratified by centre/maternal allergy) to active (n = 432) or control (n = 431) formula until 6 months of age if formula was introduced before 18 weeks. Primary outcome was cumulative incidence of eczema by 12 months in infants randomized at 0–4 weeks (375 pHF‐OS, 383 control). Secondary outcomes were cumulative incidence of eczema by 12 or 18 months in all infants randomized, immune markers at 6 months and adverse events.ResultsEczema occurred by 12 months in 84/293 (28.7%) infants allocated to pHF‐OS at 0‐4 weeks of age, vs 93/324 (28.7%) control (OR 0.98 95% CI 0.68, 1.40; P = 0.90), and 107/347 (30.8%) pHF‐OS vs 112/370 (30.3%) control in all infants randomized (OR 0.99 95% CI 0.71, 1.37; P = 0.94). pHF‐OS did not change most immune markers including total/specific IgE; however, pHF‐OS reduced cow's milk‐specific IgG1 (P < 0.0001) and increased regulatory T‐cell and plasmacytoid dendritic cell percentages. There was no group difference in adverse events.ConclusionpHF‐OS does not prevent eczema in the first year in high‐risk infants. The immunological changes found require confirmation in a separate cohort.
A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency To the Editor:Recently, a novel syndrome of combined immunodeficiency, allergy, and ''auto''inflammation caused by mutations in the ARPC1B gene has been reported. [1][2][3][4] Analysis of patient-derived
Background: Persistent crying in infancy is common and may be associated with gastroesophageal reflux disease (GERD) and/or non-IgE-mediated cow's milk protein allergy (CMPA). We aimed to document upper gastrointestinal motility events in infants with CMPA and compare these to findings in infants with functional GERD. Methods: Infants aged 2 to 26 weeks with persistent crying, GERD symptoms and possible CMPA were included. Symptoms were recorded by 48-hour cry-fuss chart and validated reflux questionnaire (infant GERD questionnaire [IGERDQ]). Infants underwent a blinded milk elimination-challenge sequence to diagnose CMPA. GERD parameters and mucosal integrity were assessed by 24-hour pH-impedance monitoring before and after cow's milk protein (CMP) elimination. 13C-octanoate breath testing for gastric emptying dynamics, dual-sugar intestinal permeability, fecal calprotectin, and serum vitamin D were also measured. Results: Fifty infants (mean age 13 ± 7 weeks; 27 boys) were enrolled. On the basis of CMP elimination-challenge outcomes, 14 (28%) were categorized as non-IgE-mediated CMPA, and 17 (34%) were not allergic to milk; 12 infants with equivocal findings, and 7 with incomplete data were excluded. There were no baseline differences in GERD parameters between infants with and without CMPA. In the CMPA group, CMP elimination resulted in a significant reduction in reflux symptoms, esophageal acid exposure (reflux index), acid clearance time, and an increase in esophageal mucosal impedance. Conclusions: In infants with persistent crying, upper gastrointestinal motility parameters did not reliably differentiate between non-IgE-mediated CMPA and functional GERD. In the group with non-IgE-mediated CMPA, elimination of CMP significantly improved GERD symptoms, esophageal peristaltic function, and mucosal integrity.
The accepted version of an article is the version that incorporates all amendments made during the peer review process, but prior to the final published version (the Version of Record, which includes; copy and stylistic edits, online and print formatting, citation and other linking, deposit in abstracting and indexing services, and the addition of bibliographic and other material.Self-archiving of the accepted version is subject to an embargo period of 12-24 months. The embargo period is 12 months for scientific, technical, and medical (STM) journals and 24 months for social science and humanities (SSH) journals following publication of the final article.• the author's personal website • the author's company/institutional repository or archive • not for profit subject-based repositories such as PubMed Central Articles may be deposited into repositories on acceptance, but access to the article is subject to the embargo period. The version posted may not be updated or replaced with the final published version (the Version of Record). Authors may transmit, print and share copies of the accepted version with colleagues, provided that there is no systematic distribution, e.g. a posting on a listserve, network or automated delivery.There is no obligation upon authors to remove preprints posted to not for profit preprint servers prior to submission. March, 2017 Accepted ArticleThis article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/cea.12608 This article is protected by copyright. All rights reserved. Accepted ArticleThis article is protected by copyright. All rights reserved. Key wordsAllergy prevention; cytokines; eczema; egg allergy; egg protein; infancy.
All Rights ReservedNo part of this work may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording or otherwise, without written permission from the Publisher, with the exception of any material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. ABSTRACT AbstractIn this book, switched-capacitor (SC) techniques are proposed which allow the attainment of higher intrinsic analogue accuracies than previously possible in such application areas as analogue filter and analogue-to-digital converter (ADC) design. The design philosophy is to create the required functionality without relying on trimming or digital calibration means but instead to develop methods which have reduced dependence on both component matching (especially capacitor matching) and parasitic effects (especially parasitic capacitance).At a system level, orthogonal design procedures are employed which ensure that artefacts due to expected circuit imperfections are avoided in the system transfer function. For instance, in SC filter design, orthogonal-hardware-modulation helps alleviate the effects of Npath mismatch through the introduction of an extra degree of freedom, where the number of hardware paths N (hardware modulation) is decoupled from the functional modulation factor n, as introduced by the transformation . In algorithmic ADC design, both cyclic and pipelined, conventional techniques make use of multiplying digital-to-analogue converters (or MDACs) which require SC circuits with accurate capacitor ratios to implement accurate signal multiplication. On the other hand, in this book, the ADC function is decomposed into the simple sub-functions of signal addition and level shifting which can be implemented using SC techniques which don't rely on accurate capacitor ratios.At circuit level, delta-charge flow techniques are employed to realize SC circuits with more accurate transfers than their conventional charge-transfer (QT) counterparts. Unlike QT SC circuits, SC circuits do not require signal charge transfer from capacitor to capacitor via the amplifier virtual earth node. Instead, only a delta charge flows in the virtual earth node due to the presence of parasitic capacitors at the amplifier input terminals. In SC filter design, delta-charge-redistribution is a means for the accurate implementation of filter transfer functions using passive charge redistribution between capacitors in the feedback path of an amplifier, instead of active charge transfer between capacitors through the active intervention of an amplifier in QT SC filters. In ADC design, a highly accurate method (C+C) for the stacking of capacitor voltages is proposed which uses a floating-hold-buffer for implementation. The accuracy of signal addition is practically insensitive to the matching and linearity of the signal capacitors as well as the presence of parasitic terminal capacitance.A number of ...
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
334 Leonard St
Brooklyn, NY 11211
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.