Background: Abnormal uterine bleeding is one of the most common problems among pre and postmenopausal women. Virtually every woman will at some point in her lifetime experiences episodes of bleeding that are perceived as abnormal. Menstrual abnormalities are the cause of discomfort, inconvenience and disruption of healthy social and physical lifestyles among millions of women worldwide. Dysfunctional uterine bleeding is an abnormal bleeding from uterus in the absence of an organic pathology to account for. It commonly occurs in reproductive and perimenopausal age groups. When no systemic or local pelvic cause is evident to the clinician, histopathological examination of the endometrial biopsies remains the only alternative to reach the diagnosis. The following study intends to find out the incidence of various etiopathological factors in cases of dysfunctional uterine bleeding and to study the efficacy of Homoeopathic Medicines in cases of DUB.Methods: 30 cases fitting the case definition were studied. Female patients above 35yrs. age showing abnormal bleeding from the uterus without any underlying pathology were selected for the study. Pregnant women, females below 35yrs., showing abnormal finding on USG were excluded from the study. Criteria for assessment were laid down and scoring was done and analyzed.Results: Scoring was done before treatment and after treatment, t- test was applied. Null and alternative hypothesis were laid down. From the value of t-test, we reject the null hypothesis and accept the alternative hypothesis.Conclusions: Homoeopathic medicines Sabina, Cimicifuga and Thalaspi Bursa were found effective in management of cases of DUB.
Background: Antioxidants are rampantly studied due to their ability to trap the free radicals. Due to excessive stress these free radicals take part as fundamental components in oxidative damage leading to changes in SOD, CT, GSSH, GPx, GSH, LPO, GGT, LDH. High Dilution Medicines (HDM) are also being investigated in deciphering their antioxidant properties. Methodology: The database for the research paper was screened from Google scholar, PubMed, and Web of Science. The search keywords used were Antioxidant, Homoeopathy, Homeopathy, In-vitro, In-vivo, Clinical trial in various permutation and combinations. The research article in original full text with English language is included in this manuscript. Score for assessment of biological experiment on homeopathy (SABEH) was referred for screening the research articles. Results: Around 14 research manuscript showed the research conducted on HDM with respect to their antioxidant properties. Four In-vitro, Eight In-vivo studies and two Clinical studies were used in assessing the antioxidant activity. Out of 14, only 12 studies were included in SABEH criteria scores above 5/9. SOD, CT, GSH, GPx, LPO, GSSH, GGT, LDH, 2,2 DPPH were found to be explored with HDM with their antioxidant properties. Conclusion: HDM can further be studied at to what extent they provide preventive role, interception role and repair role pertaining with their antioxidant properties, also comparing the efficacy of antioxidant properties through oral route and injectable in various stages of disease.
<p class="abstract"><strong>Background:</strong> Arthritis and rheumatism are among the commonest forms of chronic disease and, with an aging population, are set to become commoner still. Strictly speaking, arthritis means disease of the joints, while rheumatism is disease of the soft connective tissues which support and move the joints. There are many problems with current conventional treatment of arthritis and rheumatism. Although the new generation of NSAIDs is safer, they are only glorified painkillers, which do not affect the basic disease process. Similarly for rheumatoid arthritis, a range of powerful drugs is available but all of these have long and alarming lists of side effects. Thus the main aim of this research study is to prove the efficacy of Homoeopathy in managing cases of Osteoarthritis without any side-effects<span lang="EN-IN">.</span></p><p class="abstract"><strong>Methods:</strong> 30 cases were selected fitting the case definition. Age group of 45-79 years was chosen for the study. Inclusion and exclusion criteria were laid down. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and <strong>Kellgren and Lawrence system</strong><span class="apple-converted-space"> of</span> classifying the severity of knee-osteoarthritis<strong> </strong>were used to assess the severity and outcome.<strong></strong></p><p class="abstract"><strong>Results:</strong> All the results were tabulated. Graphical presentation was made of all the observations. Scores before and after treatment was compared. It was found that there was vast difference in scores before and after treatment<span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> Rhus tox was found to be effective in managing cases of Osteoarthritis of Knee Joint<span lang="EN-IN">.</span></p>
Ignatia contains a considerable amount of strychnine and Brucine, more indeed in proportion than Nux Vomica. It is these alkaloids that it owes much of its energy. In poisonous quantities, Ignatia causes tetanic spasms while in small doses, it cures the same symptoms. Ignatia exalts the impressionability of the incident nerves all over the body. It causes reflex excitation- twitching, constrictions, and spasms. This action is not deep and long lasting. Alternate set of symptoms are numbness, torpor. Ignatia acts specially on the Medulla oblongata and spinal nervous system giving rise to these tetanic convulsions. The entire nervous system gets affected making the system sensitive so much that there is intense acuteness of the nerves of sensation and of special senses and increased susceptibility of external impressions, mental and physical. If we were to correlate this with the pharmacological action of Strychnine and Brucine, all the actions of Ignatia can aptly be assigned to the pharmacological action of these two active principles. This can be verified by High Performance Thin Layer Chromatography which would help to segregate and identify the constituents present in the Ignatia Amra mother tincture and correlate their action with the pharmacological action of Ignatia Amra. Materials and Methods: Standard Ignatia Amara mother tincture was tested for its alkaloid markers and its correlation with the pharmacological action was studied. High Performance Thin Layer Chromatography was used for qualitative analysis if Ignatia Amra homoeopathic mother tincture. TLC Aluminium sheets with silica gel 60 F253 pre-coated layer (20cm x 10cm), thickness-0.2mm, no. of tracks-18, band length-6mm constituted the stationary phase. Chloroform: Methanol (9.5:0.5) constituted the mobile phase. The plate was developed in developing chamber and observed under U.V. Light. Results: Rf. Values of the Ignatia Amara homoeopathic mother tincture were observed at 0.67 and 0.70 which corresponds to the Rf. Value of Brucine which is 0.69. Superimposed UV Spectra of brucine standard shows y-max at 306nm whereas superimposed UV Spectra of strychnine standard shows y-max at 259nm which matches with the y-max shown by Ignatia Amra mother tincture one at 260nm and other at 306nm. Conclusion: Thus, it is evident from the chromatogram that Ignatia Amara homoeopathic Mother tincture contains both Brucine and Strychnine which is supported by evidence in the source books. This helps correlate the action of Ignatia Amara homoeopathic mother tincture with its active principles namely Brucine and Strychnine.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.