We report the first case of unilateral spontaneous Descemet membrane detachment (DMD) with tear occurring in a patient with osteogenesis imperfecta (OI). A 20-year-old male patient with OI presented with a history of recent primary repair (2 weeks prior) of left globe rupture following local finger trauma to the left eye. The patient had no history of other ocular surgery or trauma. The examination revealed a best corrected visual acuity of 20/40 in the right and no light perception in the left eye. Slit-lamp examination showed an oval giant Descemet tear extending from the 12 o’clock to the 5 o’clock area and a large DMD involving the upper and nasal quadrants in the right cornea. It was thought that monitoring the patient without intervention and only considering a surgical procedure if the disorder progressed was the best option, taking into account the patient’s reasonable visual acuity and the risks of keratoplasty. The dimensions of the DMD and tear had remained the same at 1-year follow-up period. We believe that follow-up without intervention should be considered for non-progressive DMD with a giant tear if the patient has a single functional eye.Electronic supplementary materialThe online version of this article (doi:10.1007/s40123-015-0034-2) contains supplementary material, which is available to authorized users.
Aim: To evaluate the mean changes in corneal endothelial cells in eyes that operated under sevoflurane general anesthesia. Material and Methods: 32 eyes of 32 patients who had extraocular surgery under general anesthesia included in this prospective study. Cell density (CD), Coefficient of Variation (CV) and Hexagonality rate (Hex) specular microscopy results at before surgery and 1 week and 1 month after surgery were analyzed. Results: The mean age of the patients was 15 ± 10 (min 4-max 36). The mean operation time of the patients was 90 ± 15 minutes. The mean preoperative CD value of the study subjects was 3097±15 cell/mm2. The mean postoperative CD value was 3119±194 cell/mm2 at the 1.week and 3120±207 cell/mm2 at the 1.month (p=0.678). The mean preoperative CV was 0.27±0.4 while the postoperative 1. week value was 0.27±0.4, and the postoperative 1st month value was 0.27±0.5 (p=0.319). The mean preoperative Hex value of the study subjects was 53±10%. The mean postoperative Hex value was 54±11% at the 1.week and 55±10% at the 1.month (p=0.992). No significant difference was present between the periods in terms of CD, CV and Hex. Conclusion: There is no change in the corneal endothel in patients who suffered general anesthesia with sevoflurane.
Purpose To evaluate contrast sensitivity in patients with Behçet's disease (BD) without ocular involvement. Methods The study group was composed of 47 BD patients (20 to 50 years of age) who did not have ocular involvement. The control group was composed of 47 normal volunteers who were similar to the study group in terms of age and gender. No participants in this study had any ocular or systemic pathologies except for BD. The contrast sensitivity measurements were performed using the Functional Acuity Contrast Test under photopic conditions, and the results were compared between the two groups. Results The mean age of the BD patients and control subjects was 34.5 ± 9.7 and 33.2 ± 7.6 years, respectively. The mean disease duration of the BD patients was 5.5 ± 6.4 years. There was a statistically significant decrease at five spatial frequencies (A, 1.5; B, 3; C, 6; D, 2; and E, 18 cycles per degree) in patients with BD compared with control subjects ( p < 0.001, p = 0.004, p = 0.002, p < 0.001, and p = 0.001, respectively). Conclusions The contrast sensitivity of BD patients without ocular involvement was lower than that of the control group. Further studies seem mandatory to confirm our results.
egener granülamatözü (WG); otoimmün kaynaklı olduğu düşü-nülen üst ve alt solunum yollarının nekrotizan granülomatözü, fokal segmental glomerülonefrit, küçük arter ve venlerin nekrotizan vasküliti ile karakterizedir.1 WG en sık 5. dekaddaki erkek hastaları etkilemekte ve bu hastalarda göz tutulumunun %50-60 oranında olduğu tahmin edilmektedir.1,2 Hastaların %8-16'sında hastalığın ilk ortaya çıkış şekli olabilen göz tutulumu önemli bir morbidite sebebidir ve en sık orbita tutulmasına karşın tars-konjonktiva, sklera, kornea, retina, koroid, nazolakrimal kanal ve optik sinir etkilenebilmektedir.
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