Surgical treatment of female genital cancer remains a rather difficult task in gynecological practice due to the possibility of thrombotic complications. It is important to study the features of hemostasis in such patients for the practical application of this knowledge. The aim of the study was to scientifically substantiate the features of hemostasis in patients with female genital cancer. Study materials: 103 patients with genital cancer who were treated. The purpose of the study. Coagulogram, colorimetry, others. Results of the research. As a result of a blood test, it was found that the initial level of hemoglobin in patients with thrombotic complications after surgery decreased by 12%, in patients without thrombotic complications – by 14%. The average platelet count in patients with thrombotic complications decreased by 11,50%, in patients without thrombotic complications – 8,12%. The level of leukocytes in patients with thrombotic complications – increased by 21,05%, in patients without thrombotic complications – 30,30%. In the study of hemostasis, it has been found that surgery in patients with female genital cancer causes a pronounced activation of the hemostasis system, especially in patients with thrombotic complications. In patients with thrombotic complications there is a more pronounced activation of intravascular coagulation on the background of a significant decrease in the level of antigen III than in patients without thrombotic complications. The level of fibrinogen in patients with thrombotic complications in the preoperative period was significantly higher by 16,3% than in patients without thrombotic complications; there was a decrease in fibrinogen levels in the early postoperative period; from the third day after surgery, fibrinogen levels increased in patients without thrombotic complications. There was also a significant reduction in activated partial thromboplastin time in patients with thrombotic complications. The number of soluble complexes of fibrin monomers increased to higher values in patients with thrombotic complications. Conclusion. In the study of hemostasis, it has been found that surgery in patients with female genital cancer causes marked activation of the hemostasis system, especially in patients with thrombotic complications.
Deep vein thrombosis (DVT) is a medical condition, occurs when a blood clot forms in a deep vein and pulmonary embolism (PE) occurs when a blood clot gets lodged in an artery in the lung, affecting blood flow to part of the lung.The frequencies of using computed tomography (CT) and magnetic resonance imaging (MRI) to diagnose deep venous thrombosis and pulmonary embolism is increasing day by day.Both the technics are noninvasive and provide prompt results. But there are a good number of alternative technics for the same purposes. That is why, till now scholars and respective professionals are interested to know more about the justification and comparative effectiveness of CT and MRI in detecting DVT and PE.This review aimed to analyze the history of several detecting methods for DVT and PE and to dig out the clear concepts about the effectiveness and patient compliances of CT and MRI in detecting deep venous thrombosis and pulmonary embolism. For proper analysis a lot of research as well as meta-analysis had been studied.From this article besides scholars and professionals, general readers will get a clear concept about the features, effectiveness and justifications of CT and MRI in treating DVT and PE.
Thrombosis is a common complication in cancer patients. In all cancer patients, changes occur that lead to arterial and venous thrombosis. It is not known for certain what exactly provokes the appearance of blood clots and causes disseminated intravascular coagulation (DIC). A morpho-histological study of the muscles of the lower extremities was carried out in two groups of people who suffered from cancer and had deep vein thrombosis of the lower extremities with subsequent migration of blood clots. In two groups of people who died due to the migration of blood clots from the veins of the lower extremities in the pulmonary artery, clear dystrophic changes in muscle fibers were found with narrowing of all arterioles and a strong expansion of the venous vessels. In all the venous vessels of the preparation, damage to the endothelium was found, which may indicate the presence of thrombosis of the venous vessels carrying blood from the muscles. People with cancer of the pancreas and/or colon have significant hemodynamic, hypertrophic, dystrophic, and atrophic changes in muscle fibers. There are signs of a systemic effect of the tumor on the vessels and hemodynamics in the lower extremities.
Ungarn gehört zu jenen Ländern, die im Dezember 1991 als erste die unabhängige Ukraine anerkannt haben und mit denen Kyjiw diplomatische Beziehungen aufnahm. Bis 2017 zeichnete sich das bilaterale Verhältnis weder durch große Freundschaft noch durch Feindseligkeit aus. Meist standen die Interessen der ungarischen Gemeinschaft im Zentrum, die im äußersten Westen der Ukraine entlang der Grenze zu Ungarn in der Region Transkarpatien lebt. Seit September 2017 jedoch, nachdem in der Ukraine ein neues Bildungsgesetz verabschiedet worden war, kam es zwischen Kyjiw und Budapest zu einem heftigen Konflikt, der längst über reine Debatten zur Frage der Unterrichtssprache der ungarischen ethnischen Minderheit hinausgewachsen ist. Es entwickelte sich die schwerste und tiefgreifendste Krise zwischen den beiden Nachbarländern, seit die diplomatischen Beziehungen aufgenommen wurden. Zudem reicht diese Krise weit über die bilateralen Beziehungen hinaus und wird regelmäßig auf NATO-und EU-Ebene erörtert. Sämtliche Versuche der letzten drei Jahre, den Konflikt zwischen Kyjiw und Budapest zu lösen, blieben ohne Erfolg. Es stellt sich die Frage: Können die Ukraine und Ungarn aus der jetzigen Sackgasse herauskommen, und wenn ja, wie genau? Kostenlose E-Mail-Dienste: Länder-Analysen Die Länder-Analysen bieten regelmäßig im kostenlosen Abonnement kompetente Einschätzungen aktueller politischer, wirtschaftlicher, sozialer und kultureller Entwicklungen in Ostmitteleuropa und der GUS. Alle Länder-Analysen verstehen sich als Teil eines gemeinsamen Projektes, das der wissenschaftlich fundierten, allgemeinverständlich formulierten Analyse der Entwicklungen im östlichen Europa, der Offenheit für verschiedene inhaltliche Positionen und der kostenlosen und nicht-kommerziellen Information einer breit verstandenen interessierten Öffentlichkeit verpflichtet ist. Autor/innen sind internationale Fachwissenschaftler/innen und Expert/innen. Die Redaktionen der Länder-Analysen bestehen aus Wissenschaftler/innen mit langjähriger Forschungserfahrung. Die deutschsprachigen Länder-Analysen werden gemeinsam von der Forschungsstelle Osteuropa an der Universität Bremen, dem Zentrum für Osteuropa-und internationale Studien, der Deutschen Gesellschaft für Osteuropakunde, dem Deutschen Polen-Institut, dem Leibniz-Institut für Agrarentwicklung in Transformationsökonomien und dem Leibniz-Institut für Ost-und Südosteuropaforschung herausgegeben. Die englischsprachigen Länder-Analysen erscheinen in Kooperation der Forschungsstelle Osteuropa mit dem Center for Security Studies (CSS) der ETH Zürich. Die Länder-Analysen bieten regelmäßig Kurzanalysen zu aktuellen Themen, ergänzt um Grafiken und Tabellen sowie Dokumentationen. Zusätzlich gibt es eine Chronik aktueller Ereignisse.
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