Relationships between discharge and suspended sediment are very complex in most Mediterranean catchments. In the case of the Arnas catchment (Central Spanish Pyrenees), with a long history of human activity, the main factors that explain the variability of suspended sediment concentration (SCO during floods are the peak flow and the intensity of precipitation. A cluster analysis distinguishes four types of floods according to different characteristics of precipitation, discharge, suspended sediment transport and antecedent moisture conditions. G1 and G2 floods occur under dry conditions (which prevail most of the year), with moderate rainfall and low precipitation intensity; the discharge and suspended sediment response are very fast but limited in intensity. This suggests that the origin of water and sediment is restricted to areas located very close to the channel. G3 floods also occur under dry conditions, although during Intense rainfall events; then the response in both discharge and suspended sediment is very high, showing an enlargement of the contributing areas. Under very wet conditions (G4 floods) relatively moderate precipitation produces a very high response in discharge, but suspended sediment concentration records moderate values due to the effect of dilution when the entire catchment is contributing. IntroductionMedilemiiiean water resources mainly depend on the hydromorphological functioning of the watersheds in mountainous areas (Thornes 1999). The strategic impoitance of the latter has spurred the development of research projects which try to understand runoff generation and sediment yield, along with the temporal variability of runoff and sediment contributing areas in a changing scenario. Mediterranean areas are subject to large-scale land-use changes like farmland abandonment of steep cultivated slopes (Lasanta-Marti'nez et al, 2005), plant colonisation of the old field.s (Molinillo et at. 1997), reforestation (Ortigosa et at. 1990, and enlargement of .ski resorts. How these complex proces.ses affect the quality and quantity of waier resources, reservoir siltation and the dynamics of fluvial channels is a key question for understanding the characteristics and temporal trends of water resources in Mediterranean basins.

Abstract:The temporal and spatial dynamics of groundwater was investigated in a small catchment in the Spanish Pyrenees, which was extensively used for agriculture in the past. Analysis of the water table fluctuations at five locations over a 6-year period demonstrated that the groundwater dynamics had a marked seasonal cycle involving a wetting-up period that commenced with the first autumn rainfall events, a saturation period during winter and spring and a drying-down period from the end of spring until the end of the summer. The length of the saturation period showed great interannual variability, which was mainly influenced by the rainfall and evapotranspiration characteristics. There was marked spatial variability in the water table, especially during the wetting-up period, which could be related to differences in slope and drainage area, geomorphology, soil properties and local topography. Areas contributing to runoff generation were identified within the catchment by field mapping of moisture conditions. Areas contributing to infiltration excess runoff were correlated with former cultivated fields affected by severe sheetwash erosion. Areas contributing to saturation excess runoff were characterized by a marked spatial dynamics associated with catchment wetness conditions. The saturation spatial pattern, which was partially related to the topographic index, was very patchy throughout the catchment, suggesting the influence of other factors associated with past agricultural activities, including changes in local topography and soil properties. The relationship between water table levels and stream flow was weak, especially during the wetting-up period, suggesting little connection between ground water and the hydrological response, at least at some locations. The results suggest that in drier and human-disturbed environments, such as sub-Mediterranean mountains, saturation patterns cannot be represented only by the general topography of the catchment. They also suggest that groundwater storage and runoff is not a succession of steady-state flow conditions, as assumed in most hydrological models.

The aim of this paper was to discuss the embryological aspects of Müllerian duct anomalies and to analyze the current diagnostic methods and therapy.Müllerian anomalies are congenital defects of the female reproductive tract resulting from failure in the development of the Müllerian ducts and their associated structures. Their cause has yet to be fully clarified, and it is currently believed to be multifactorial. Symptoms appear principally during adolescence or early adulthood, and affect the reproductive capacity of these women. When clinically suspected, investigations leading to diagnosis include imaging methods such as hysterosalpingography, ultrasonography and magnetic resonance. The classification of these malformations relates to their embryogenesis, and defines the therapy and prognosis. Müllerian anomalies consist of a wide range of defects that may vary from patient to patient.Therefore, their management must also be individual, taking anatomical and clinical characteristics into consideration, as well as the patient's wishes. RESUMOO objetivo deste trabalho foi discutir as malformações müllerianas desde seus aspectos embriológicos, analisando os atuais métodos diagnóstico e terapêuticos. As malformações müllerianas são anomalias congênitas do trato reprodutivo feminino decorrentes de falha do desenvolvimento dos ductos de Müller e estruturas associadas. Sua causa não foi completamente elucidada, acreditando-se, atualmente, que seja multifatorial. Os sintomas se manifestam, principalmente, durante a adolescência e início da vida adulta, e afetam a capacidade reprodutiva dessas mulheres. A partir da suspeita clínica, a investigação diagnóstica inclui métodos de imagem, como a histerosalpingografia, ultrassonografia e ressonância magnética. A classificação das malformações está relacionada à sua embriogênese e direciona a terapêutica e prognóstico. As malformações müllerianas são um grupo amplo de anomalias que variam de paciente para paciente. Portanto, sua abordagem também é individual, devendo-se considerar os aspectos anatômicos, clínicos e o desejo da paciente.

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Background: The early identification of individuals at high risk for adverse outcomes by a Comprehensive Geriatric Assessment (CGA) in resource-limited primary care settings enables tailored treatments, however, the evidence concerning its benefits are still controversial. The main objective of this study was to examine the validity and reliability of the "Multidimensional Assessment of Older People in Primary Care (AMPI-AB)", a CGA for primary care in resource-limited settings. Methods: Longitudinal study, with median follow-up time of 16 months. Older adults from a public primary care unit in São Paulo, Brazil, were consecutively admitted. Reliability was tested in a sample from a public geriatric outpatient clinic. Participants were classified by the AMPI-AB score as requiring a low, intermediate or high complexity of care. The Physical Frailty Phenotype was used to explore the AMPI-AB's concurrent validity. Predictive validity was assessed with mortality, worsening of the functional status, hospitalizations, emergency room (ER) visits and falls. The area under the ROC curve and logistic regression were calculated for binary outcomes, and a Cox proportional hazards model was used for survival analysis.(Continued on next page)

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Background. Understanding the hospital impact of influenza requires enriching epidemiological surveillance registries with other sources of information. The aim of this study was to determine the validity of the Hospital Care Activity Record – Minimum Basic Data Set (RAE-CMBD) in the analysis of the outcomes of patients hospitalised with this infection. Methods. Observational and retrospective study of adults admitted with influenza in a tertiary hospital during the 2017/2018 and 2018/2019 seasons. We calculated the concordance of the RAE-CMBD with the influenza epidemiological surveillance registry (gold standard), as well as the main parameters of internal and external validity. Logistic regression models were used for risk adjustment of in-hospital mortality and length of stay. Results. A total of 907 (97.74%) unique matches were achieved, with high inter-observer agreement (ƙ=0.828). The RAE-CMBD showed a 79.87% sensitivity, 99.72% specificity, 86.71% positive predictive value and 99.54% negative predictive value. The risk-adjusted mortality ratio of patients with influenza was lower than that of patients without influenza: 0.667 (0.53-0.82) vs. 1.008 (0.98-1.04) and the risk-adjusted length of stay ratio was higher: 1.15 (1.12-1.18) vs. 1.00 (0.996-1.001). Conclusion. The RAE-CMBD is a valid source of information for the study of the impact of influenza on hospital care. The lower risk-adjusted mortality of patients admitted with influenza compared to other inpatients seems to point to the effectiveness of the main clinical and organisational measures adopted

RESUMEN. Este trabajo muestra que las relaciones entre precipitación y escorrentía a escala de crecida en una pequeña cuenca de campos abandonados no