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Background: The risk for developing diabetic complications are related to glycemic control which is measured by estimating the glycated hemoglobin (HbA1c) level. Calcium increases the GLUT 4 activity. Change in calcium alters the insulin receptor phosphorylation, and decreases the activity of glucose transporter Objective: To nd out the correlation between serum Calcium and glycated Haemoglobin in Type 2 Diabetes Mellitus patients. Materials And Methodology: A cross sectional study which included 100 type 2 Diabetes mellitus patients, divided into 2 groups based on HbA1c levels. Group 1 : Type 2 Diabetic patients with HbA1c more than 7 percent and Group 2 : Type 2 Diabetic patients with HbA1c less than 7 percent. Total calcium level was correlated with glycated hemoglobin level. Statistical analysis was done using unpaired t test. Result: The mean value of serum total calcium was lower in the diabetic group whose HbA1c was > 7 (p value – 0.000) when compared to the diabetic group whose HbA1c was <7. A strong negative correlation (r = -0.391) between calcium and HbA1c in the T2 diabetic patients with HbA1c >7 (p = 0.000) was observed. Conclusion: Alteration in calcium levels will have adverse effects on insulin secretion and release. Estimating the level of calcium becomes important to know the status of insulin in diabetic patients and correlating the levels of HbA1c and Serum Calcium in Type 2 DM patients, can monitor the levels of glycemic control and the risk of development of complications. Calcium supplementation to the diabetic patients can help in better glycemic control and prevent diabetes related complications

Background: Diabetes mellitus (DM) is a metabolic disorder with hyperglycemia. Dyslipidemia associated with DM patient and contributing to atherovascular events and increases the likelihood of cardiovascular disease (CVD) in future. Measurement of inflammatory marker like hs-CRP will improve the prediction of the risk of these events. This study aimed to assess the cardiac risk indices and determine their association with hs-CRP in diabetic patients. Aims and Objectives: This study is aimed to assess the association of the cardiac risk indices and hs-CRP in diabetic patients. Materials and Methods: This study included each 125 subjects of Type 2 diabetic patients and healthy control. The anthropometric parameters (BMI and WHR) and blood parameters such as fasting glucose, glycosylated hemoglobin (HbA1c), lipid profile (total cholesterol, TGL, HDL, and LDL), hs-CRP, and microalbumin were measured. Cardiac risk indices calculated from lipid profile. Results: High cardiac risk indices were observed in diabetic subjects. The cardiac risk indices were showed that significant positive correlation with BMI, fasting sugar, HbA1c, total cholesterol, TGL, LDL and HDL shows negative correlation. Furthermore, hs-CRP and microalbumin showed significant positive correlation with cardiac risk indices in Type 2 DM patients. Conclusion: The increased in values of cardiac risk indices in diabetic patients shows increasing the susceptibility of CVD in these patients in future. The correlation of indices values with hs-CRP (inflammatory marker)shows the direct association of inflammation with CVD risks in Type 2 DM patients. Screening of these indices among diabetic patients will help the propensity of future development of CVD which can be arrested by encouragement of healthy lifestyle.