A correlative study of HbA1C and lipid profile parameters among type 2 diabetic population in a rural hospital in puducherry.

Muraliswaran, P; Elamathi, T.; P, Kanagavalli; Radhika, G.

doi:10.9790/0853-1509125963

Cited by 2 publications

(2 citation statements)

References 19 publications

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“…One African study on type 2 Diabetes Mellitus patients showed that 35% had increased total serum cholesterol levels, and a study in England found that 73% had increased total serum cholesterol levels. 17 This is similar to the results of our study in which both diabetic groups have raised cholesterol levels. However, more raised in patients with more HbA1c value.…”

Section: Discussionsupporting

confidence: 91%

“…This result is similar to a study conducted on the correlation of lipid profile and HbA1c in India which showed a significant correlation between HbA1C and lipid profile parameters between the two groups (less than 7% and more than 7% of HbA1C). 17 Similarly, a study by Khan HA, et al, showed the impact of glycemic control on various lipid parameters in which severity of dyslipidemia increase in patients with higher HbA1C value, 18 which is similar to the results of this study. One African study on type 2 Diabetes Mellitus patients showed that 35% had increased total serum cholesterol levels, and a study in England found that 73% had increased total serum cholesterol levels.…”

Section: Discussionsupporting

confidence: 89%

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Association of Neutrophil to Lymphocyte and Platelet To Lymphocyte ratio with Blood Glucose Regulation in Type 2 Diabetes Patients

Ahmed¹,

Khalid²,

Munir³

et al. 2021

JRMC

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INTRODUCTION: Diabetes is characterized by chronic hyperglycemia with disturbances of carbohydrate, protein and lipid metabolism. Disorders of lipid metabolism are common in diabetes causing greater cardiovascular risks. Leukocytosis is a major marker of metabolic syndrome. Both neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) are related to subclinical inflammation worsening the glycemic control. HbA1c is used as a marker of blood glucose regulation. OBJECTIVE: To investigate the association of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio with blood glucose regulation in patients with type 2 diabetes mellitus. METHODS: This comparative analytical study was conducted in Shifa International Hospital on diabetic patients. Sample size was calculated as 62 by WHO sample size calculator . Non randomized convenient sampling was used. Patients were divided into two groups according to HbA1c level taking 7% as cut off point. Full blood count, lipid profile and liver profile were carried out. Data was analyzed by SPSS version 21. Descriptive statistics were calculated for categorical variables. For quantitative normal and dispersed variables, independent student t and Mann Whitney U test were applied respectively. P Value less than 0.05 was considered significant. RESULTS: Out of total 93 patients,33 (35.4 %) were males and 60(64.5%) were females. The mean duration of disease was 8.26 ± 5.8 years. NLR and PLR were elevated in patients having poor glucose control but that difference was not significant. Significant difference between the groups was found with random blood glucose. LDL, triglycerides , cholesterol ratio, ALT and AST were raised in patients having poor glycemic control. CONCLUSION: Patients having poor blood glucose regulation have increased levels of haematological and serological parameters posing greater cardiovascular health risks to patients with type 2 diabetes

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Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 89%