The study of experimental immunohematology has led us to look into the Some of the earlier results were summarized We confine ourselves here to ob-blood groups in different species. in Dujarric de la Rivigre and Eyquem.' servations that will cover the areas not discussed by the other contributors.
Blood Groups in ChimpanzeesThe groups of the same origin previously studied by other workers were composed mainly of animals of group A and a few animals of group 0. No chimpanzee of group B has ever been identified. All the animals that we have examined possessed antigen A. This antigen is similar to the human antigen A1. A single animal possessed an antigen resembling Az , In the serum there is an agglutinin that acts on human B red blood cells at a titer of 1/16 to 1/128.These antigens have been studied in a first group of 10 chimpanzees by the technique of absorption of antibodies and agglutination of nontreated red cells. Of 10 animals, all possessed the c antigen and one only possessed the D antigen. The Coomb's test has not permitted the affirmation of the presence of the D antigen amongst the other animals, due to the presence of a low titer of heteroagglutinin in the anti-D human sera.A second group of 13 animals has permitted the affirmation of the presence of antigen c amongst all the chimpanzees and D antigen in 8 of them, but it is the technique of papainization of the red cells which reveals the maximum sensitivity of the Rh antigens (TABLE 1).The papainized red cells are agglutinated as strongly as the Rh+ human papainized red cells. This agglutiiiation was again detected with the anti-D serum diluted 1/3200 in all cases except one.All chimpanzees examined by this technique possessed an antigen D (Rho) like human D antigen, having an antigenicity stronger than the Du red cell antigen.
Summary
Among 11 lymphocyte factors defined in sheep, 9 are the products of multiple alleles at 2 closely linked loci: OLA‐A and OLA‐B. A tenth factor is the product of a gene at a third locus: OL‐X probably on the same chromosome, but in this case very distant from OLA. The last factor is the product of a gene at a fourth locus: OL‐Z, independent of OLA‐A and B.
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