SUMMARY The literature on Clostridium perfringens infections is reviewed up to 1983. An additional case is reported with bilateral clostridial infections of the eye and orbit. One eye followed the classical course of relentless panophthalmitis, amaurosis, and orbital cellulitis ending in enucleation. The second eye contained intracameral mud and gas bubbles that were removed by vitrectomy instrumentation. Subsequent removal of the toxic cataract resulted in a final aided visual acuity of 6/18, N8. This is the third report of a retained globe, and we believe the only known case where the patient was left with useful vision.

Purpose:To study the optic disc topographic measurements of normal Indian eyes using optical coherence tomography (OCT).Materials and Methods:One hundred and fifty eyes selected randomly from 150 normal Indian subjects of both sex and various age groups underwent optic disc imaging with the OCT using the fast optic disc protocol.Results:Mean ± standard deviation of the optic disc topographic measurements were: disc area 2.63 ± 0.55 mm2, cup area 0.87 ± 0.45 mm2, neuroretinal rim area 1.78 ± 0.55 mm2 and cup to disc area ratio 0.33 ± 0.15. There was no significant difference in the measurements between males and females. There was no significant correlation with respect to age and refractive errors ranging from -5.0 to +3.0 diopters of spherical equivalent.Conclusion:Our study provides a normative database for the various optic disc topographic measurements and its variations with age, sex and refractive error in normal Indian eyes using OCT.

Purpose:To compare the anterior segment parameters in photopic and scotopic conditions using anterior segment optical coherence tomography (AS OCT) in Indian eyes.Materials and Methods:One hundred eyes of 100 normal subjects of both sexes, aged 19 to 76 years, underwent anterior segment evaluation by AS OCT (Visante™ OCT). Central corneal thickness (CCT), central anterior chamber depth (ACD), pupil diameter (PD) and the temporal and nasal peripheral irido-corneal angles were assessed in photopic and scotopic conditions. These anterior segment parameters were stratified for age, sex and refractive error.Results:Mean values of the parameters measured in photopic and scotopic conditions respectively were as follows: ACD (mm) 2.88 ± 0.32, 2.89 ± 0.32 (P = 0.10); nasal angle (degrees) 28.80 ± 5.91, 22.28 ± 7.50 (P < 0.001); temporal angle (degrees) 29.95 ± 6.74, 22.82 ± 8.43 (P < 0.001); pupil diameter (mm) 4.08 ± 0.91, 4.68 ± 0.92 (P < 0.001); CCT (µm) 519 ± 33.88, 519 ± 33.88.Conclusions:There was no significant difference in the ACD in photopic and scotopic conditions. While the nasal and temporal angles showed a significant decrease, the pupil diameter showed a significant increase in scotopic conditions. Mean central ACD decreased with age and was shallower in females than in males. It was highest in myopes and lowest in hypermetropes. CCT was not influenced by photopic and scotopic conditions.

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BACKGROUND The cells of the haematopoietic system are highly radiosensitive and the medical radiographers who are exposed to chronic ionizing radiation are more prone to get haematological disorders later in life. A change in haematological profile is a warning sign for development of haematological diseases later. Even though the effect of acute radiation is well known, the effect of chronic low dose radiation on haematopoietic tissue is less known. Hence this study was undertaken to find out the effect of chronic low dose radiation among radiographers, to initiate awareness among them about the radiation effects and the importance of regular screening to prevent the ill effects of radiation. MATERIALS AND METHODS The study was conducted on 20 healthy radiographers and 20 healthy, age and sex matched control group. The subjects were enrolled based on detailed questionnaire and informed consent was taken from all the subjects. The mean age of radiographers was 37.4 years and that of control was 39.4 years. The radiographers were exposed to low dose radiation for more than 5 years and the radiation dose of radiographers who participated in the study were in the range of Annual Average Effective Dose (AAED) of 0.29-1.91 mSv. Subjects with anaemia, cardiopulmonary diseases, acute and chronic infections, history of diabetes mellitus, auto immune disease, malignancy, and history of smoking and drug addiction were excluded from the study. Control subjects who were exposed to medical or diagnostic radiation recently were also excluded from the study. The blood cell count was performed on Beckman coulter counter. The haematological parameters measured were RBC count,