Gas gangrene infection of the eyes and orbits.

Abstract

SUMMARY The literature on Clostridium perfringens infections is reviewed up to 1983. An additional case is reported with bilateral clostridial infections of the eye and orbit. One eye followed the classical course of relentless panophthalmitis, amaurosis, and orbital cellulitis ending in enucleation. The second eye contained intracameral mud and gas bubbles that were removed by vitrectomy instrumentation. Subsequent removal of the toxic cataract resulted in a final aided visual acuity of 6/18, N8. This is the third report of a retained globe, and we believe the only known case where the patient was left with useful vision.

Clostridium perfringens Endophthalmitis After Penetrating Keratoplasty With Contaminated Corneal Allografts

“…1 Intraocular inoculation of C. perfringens by trauma, surgery, or endogenous spread can result in fulminant endophthalmitis with very poor outcomes. 2,3 Specific reports of postkeratoplasty clostridial endophthalmitis due to contaminated corneal allografts are extremely rare. 2,3 Specific reports of postkeratoplasty clostridial endophthalmitis due to contaminated corneal allografts are extremely rare.…”

Clostridium perfringens Keratitis Leading to Blinding Panophthalmitis

“…Although rarely encountered as ocular pathogens, they are well-known causes of fulminant panophthalmitis from injuries with soil contamination and with retained intraocular foreign bodies. 1,2,7 More rarely, these organisms can cause endogenous endophthalmitis in the setting of perforation of the gastrointestinal tract. 8,9 The clinical picture of Clostridium panophthalmitis has been well described, 8 and with very few exceptions, 7 the outcome is loss of the eye.…”

“…1,2 Primary corneal infections are rare, and there have been very few reports in the ophthalmic literature. [3][4][5][6] When reported, corneal Clostridium infections tend not to be as destructive as intraocular infections.…”

Gas gangrene of the eye: endogenous Clostridium perfringens endophthalmitis

“…Endogenous C. perfringens endophthalmitis is blinding and has invariably led to surgical removal of the globe 1 , 2 . Our case highlights the importance of rapid vitreous microscopy and intravitreal antibiotic therapy as a globe saving measure.…”